Is 5-Methyl-Beta-Ionone safe in cosmetics?
5-Methyl-Beta-Ionone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
5-Methyl-Beta-Ionone
Also known as: 1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, beta methyl ionone, Cetone, beta-, EINECS 204-843-7, FEMA No. 2712 (+7 more)
INCI: 5-METHYL-BETA-IONONE
5-Methyl-Beta-Ionone (CAS 127-43-5) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 127-43-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(E)-1-(2,6,6-trimethylcyclohexen-1-yl)pent-1-en-3-one
InChIKey
LMWNGLDCJDIIBR-CMDGGOBGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; IFRA-regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Methyl-Beta-Ionone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
399
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
beta-CETONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
METHYL-beta-IONONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 5-Methyl-Beta-Ionone.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-
beta methyl ionone
Cetone, beta-
EINECS 204-843-7
FEMA No. 2712
beta-Ionone, methyl-
beta-Iraldeine
beta-Methylionone
NSC 163995
1-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-1-penten-3-one
5-(2,6,6-Trimethyl-1-cyclohexenyl)-4-penten-3-one
UNII-54PXU8D4R5
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 5-Methyl-Beta-Ionone allowed in the EU?
5-Methyl-Beta-Ionone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Methyl-Beta-Ionone do in cosmetics?
5-Methyl-Beta-Ionone functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 127-43-5.
Is 5-Methyl-Beta-Ionone used outside cosmetics?
5-Methyl-Beta-Ionone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 5-Methyl-Beta-Ionone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Chemical family
Fragrance (Perfuming)
Alpha-Isomethyl Ionone
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Chemical family
Fragrance ingredient
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Good
Chemical family
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