Is Benzoxiquine safe in cosmetics?
Benzoxiquine has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited. This ingredient has been reviewed by cir.
Benzoxiquine
Also known as: 5-21-03-00259, Benzoic acid, 8-quinolyl ester, Benzoxyquine, 8-Benzoyloxyquinoline, BRN 0191186 (+8 more)
INCI: BENZOXIQUINE
Benzoxiquine (CAS 86-75-9) is a cosmetic cosmetic ingredient functioning as Antimicrobial / Preservative. EU Regulation 1223/2009 status: prohibited; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 86-75-9 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial / Preservative
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not specifically listed as prohibited, but 8-hydroxyquinoline derivatives carry significant safety concerns. Not GRAS.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Benzoxiquine.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
Verdict: unknown
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for Benzoxiquine.
Regulatory Flags
preservative
Known Synonyms
5-21-03-00259
Benzoic acid, 8-quinolyl ester
Benzoxyquine
8-Benzoyloxyquinoline
BRN 0191186
Dioxyline
EINECS 201-697-6
NSC 3951
Oxyquinoline benzoate
Paveril
Benzoxiquina
Benzoxiquinum
UNII-GRE0P19C3Z
Chemical Function
Biocide
Regulatory Lists
pharmaceutical
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BENZOXIQUINE
ChEMBL ID
CHEMBL1170610
Max Phase
2
Frequently Asked Questions
Is Benzoxiquine allowed in the EU?
Benzoxiquine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzoxiquine do in cosmetics?
Benzoxiquine functions as: Antimicrobial / Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 86-75-9.
Is Benzoxiquine used outside cosmetics?
Benzoxiquine also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Benzoxiquine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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