Is Alpha-Methyl-Beta-Ionone safe in cosmetics?
Alpha-Methyl-Beta-Ionone has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted.
Good
Cosmetic Ingredient
Alpha-Methyl-Beta-Ionone
Also known as: 1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, beta methyl ionone, Cetone, beta-, EINECS 204-843-7, FEMA No. 2712 (+7 more)
INCI: ALPHA-METHYL-BETA-IONONE
Alpha-Methyl-Beta-Ionone (CAS 127-43-5) is a cosmetic cosmetic ingredient functioning as Fragrance (Perfuming). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 127-43-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Alpha-Methyl-Beta-Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317, H411).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance (Perfuming)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(E)-1-(2,6,6-trimethylcyclohexen-1-yl)pent-1-en-3-one
InChIKey
LMWNGLDCJDIIBR-CMDGGOBGSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not restricted by FDA
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Alpha-Methyl-Beta-Ionone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
399
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
beta-CETONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
METHYL-beta-IONONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Alpha-Methyl-Beta-Ionone.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-
beta methyl ionone
Cetone, beta-
EINECS 204-843-7
FEMA No. 2712
beta-Ionone, methyl-
beta-Iraldeine
beta-Methylionone
NSC 163995
1-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-1-penten-3-one
5-(2,6,6-Trimethyl-1-cyclohexenyl)-4-penten-3-one
UNII-54PXU8D4R5
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Alpha-Methyl-Beta-Ionone allowed in the EU?
Alpha-Methyl-Beta-Ionone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Alpha-Methyl-Beta-Ionone do in cosmetics?
Alpha-Methyl-Beta-Ionone functions as: Fragrance (Perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 127-43-5.
Is Alpha-Methyl-Beta-Ionone used outside cosmetics?
Alpha-Methyl-Beta-Ionone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Alpha-Methyl-Beta-Ionone have different safety status in cosmetics vs industrial chemicals?
Alpha-Methyl-Beta-Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317, H411).
Compliance Tools
Check Alpha-Methyl-Beta-Ionone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Antioxidant
5-Methyl-Beta-Ionone
Good
Chemical family
Fragrance (perfuming)
Alpha-Ionone
Good
Chemical family
Fragrance (Perfuming)
Alpha-Isomethyl Ionone
Good
Chemical family
Fragrance ingredient
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