Is Acetyl Methionine safe in cosmetics?
Acetyl Methionine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Acetyl Methionine
INCI: ACETYL METHIONINE
Acetyl Methionine (CAS 65-82-7) is a cosmetic cosmetic ingredient functioning as Skin conditioning; antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 65-82-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Acetyl Methionine is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin conditioning; antioxidant
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
InChIKey
XUYPXLNMDZIRQH-LURJTMIESA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA-approved food additive under 21 CFR 172.372; no cosmetic-specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl Methionine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
amino_acid
{"cas_number": "65-82-7", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "191", "amino_acid_composition_key": "N_acetyl_methionine", "charge_at_pH_5_5": "anionic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "poor", "moisture_binding_capacity": "moderate", "NMF_component": "no", "skin_penetration_depth": "strat…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Softener and conditioner
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl Methionine.
Regulatory Flags
cir-safe
fda-food-additive
low-ewg-hazard
amino-acid-derivative
antioxidant-activity
Chemical Function
Softener and conditioner
Flavouring and nutrient
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
active_ingredient; animal_products; Europe; pharmaceutical; residue
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; pharmaceutical
Frequently Asked Questions
Is Acetyl Methionine allowed in the EU?
Acetyl Methionine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Methionine do in cosmetics?
Acetyl Methionine functions as: Skin conditioning; antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 65-82-7.
Is Acetyl Methionine used outside cosmetics?
Acetyl Methionine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Acetyl Methionine have different safety status in cosmetics vs industrial chemicals?
Acetyl Methionine is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Acetyl Methionine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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