Is 2,6-DICARBOXYPYRIDINE safe in cosmetics?
2,6-DICARBOXYPYRIDINE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
2,6-DICARBOXYPYRIDINE
Also known as: Dipicolinate, EINECS 207-894-3, UNII-UE81S5CQ0G
2,6-DICARBOXYPYRIDINE (CAS 499-83-2) is a cosmetic cosmetic ingredient functioning as Chelating. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 499-83-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2,6-DICARBOXYPYRIDINE is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Chemistry & Identifiers
IUPAC Name
pyridine-2,6-dicarboxylic acid
InChIKey
WJJMNDUMQPNECX-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chelating agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for 2,6-DICARBOXYPYRIDINE.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
Known Synonyms
Dipicolinate
EINECS 207-894-3
UNII-UE81S5CQ0G
Chemical Function
Chelating agent
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
Raw materials
inert_ingredient; non_food_use; Pesticides
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DIPICOLINIC ACID
ChEMBL ID
CHEMBL284104
Frequently Asked Questions
Is 2,6-DICARBOXYPYRIDINE allowed in the EU?
2,6-DICARBOXYPYRIDINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,6-DICARBOXYPYRIDINE do in cosmetics?
2,6-DICARBOXYPYRIDINE functions as: Chelating. It is classified as a cosmetic ingredient in our database. CAS number: 499-83-2.
Is 2,6-DICARBOXYPYRIDINE used outside cosmetics?
2,6-DICARBOXYPYRIDINE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2,6-DICARBOXYPYRIDINE have different safety status in cosmetics vs industrial chemicals?
2,6-DICARBOXYPYRIDINE is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check 2,6-DICARBOXYPYRIDINE compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
CURCUBITURILS
Good
Same category
Absorbent, Chelating, Emulsion Stabil...
DISODIUM GLUCARATE/GLUCONATE/GLUCURONATE/GLYCOLATE/KETOGLUCONATE/OXALATE/TARTRATE/TARTRONATE
Good
Same category
Chelating
OCTYL POLYSTYRENE OXIDE/PEG-10 COPOLYMER
Good
Same category
Antistatic, Chelating
PENTETIC ACID
Good
Same category
Chelating
PHOSPHONOBUTANETRICARBOXYLIC ACID
Good
Same category
Anticorrosive, Buffering, Chelating
TETRASODIUM PYROPHOSPHATE
Good
Same category
Anticaking, Buffering, Chelating, Ora...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
2,6-Dicarboxypyridine (Dipicolinic Acid)
Good
Chemical family
Chelating agent
Carvacrol
Moderate
Chemical family
Perfuming Agent, Antimicrobial, Antio...
Hinokitiol
Good
Chemical family
Antimicrobial, anti-dandruff agent, a...
Is 2,6-DICARBOXYPYRIDINE in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for 2,6-DICARBOXYPYRIDINE in your formulation.