What is the NOAEL for 2,6-Pyridinedicarboxylic acid?
2,6-Pyridinedicarboxylic acid has 5 NOAEL studies in the database. The lowest reported value is UE81S5CQ0G UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,6-Pyridinedicarboxylic acid
Also known as: Dipicolinate, EINECS 207-894-3, UNII-UE81S5CQ0G
CAS 499-83-2
2,6-Pyridinedicarboxylic acid (CAS 499-83-2) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 2,6-Dicarboxypyridine (Dipicolinic Acid) →
Cross-Vertical Regulatory Divergence
2,6-Pyridinedicarboxylic acid is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
2,6-Pyridinedicarboxylic acid
CAS Number
499-83-2
DTXSID
DTXSID7022043
Molecular Formula
C7H5NO4
InChI Key
WJJMNDUMQPNECX-UHFFFAOYSA-N
Monoisotopic Mass
167.021858
Synonyms
DipicolinateEINECS 207-894-3UNII-UE81S5CQ0G
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Chelating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Raw materials | Air Water INC | Air Water INC |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| UE81S5CQ0G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UE81S5CQ0G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UE81S5CQ0G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UE81S5CQ0G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pyridine-2,6-dicarboxylic acid | 207-894-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DIPICOLINIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
4
Frequently Asked Questions
What regulatory lists include 2,6-Pyridinedicarboxylic acid?
2,6-Pyridinedicarboxylic acid appears on 5 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018), Raw materials, and 2 more. Source: EPA CPDat.
Is 2,6-Pyridinedicarboxylic acid used in cosmetics?
Yes, 2,6-Pyridinedicarboxylic acid is also indexed as a cosmetic ingredient under the name 2,6-Dicarboxypyridine (Dipicolinic Acid). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,6-Pyridinedicarboxylic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,6-Pyridinedicarboxylic acid have different safety status in cosmetics vs industrial chemicals?
2,6-Pyridinedicarboxylic acid is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is 2,6-Pyridinedicarboxylic acid used outside industrial chemicals?
2,6-Pyridinedicarboxylic acid also appears in cosmetics, pharmaceutical databases.