Is Yohimbe Bark Extract safe in cosmetics?
Yohimbe Bark Extract has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
Poor
Cosmetic Ingredient
Yohimbe Bark Extract
INCI: PAUSINYSTALIA YOHIMBE BARK EXTRACT
Yohimbe Bark Extract (CAS 85117-22-2) is a cosmetic cosmetic ingredient functioning as Historically claimed as skin conditioning, lipolytic agent. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 85117-22-2 →
Auto-generated CPSR Part A draft with source citations
Function
Historically claimed as skin conditioning, lipolytic agent
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Not specifically listed on FDA's prohibited list, but yohimbine is a pharmacologically active alkaloid (α2-adrenergic antagonist). Any cosmetic containing it must still meet general safety standards; use in cosmetics is highly problematic
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Yohimbe Bark Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Yohimbe Bark Extract.
Regulatory Flags
plant-extract
Chemical Function
Humectant
Softener and conditioner
Frequently Asked Questions
Is Yohimbe Bark Extract allowed in the EU?
Yohimbe Bark Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Yohimbe Bark Extract do in cosmetics?
Yohimbe Bark Extract functions as: Historically claimed as skin conditioning, lipolytic agent. It is classified as a cosmetic ingredient in our database. CAS number: 85117-22-2.
Compliance Tools
Check Yohimbe Bark Extract compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
Excellent
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Excellent
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
Excellent
Same category
Skin Conditioning
Acetylneuraminic Acid
Excellent
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
Excellent
Same category
Skin Conditioning, Hair Conditioning;...
1,2,4-Benzenetriacetate
Poor
Similar safety
Hair dye precursor (triacetyl ester o...
1,2,4-Trihydroxybenzene
Poor
Similar safety
Hair colorant (auto-oxidative dye)
1,3-Bis-(Isocyanatomethyl) Cyclohexane
Poor
Similar safety
Monomer / cross-linking agent used in...
1,4-Butanediol
Poor
Similar safety
Solvent, humectant, viscosity control...
1,6-Hexamethylene Diisocyanate (HDI)
Poor
Similar safety
Monomer and crosslinker in polymer sy...
1,6-Hexanediamine
Poor
Similar safety
Industrial chemical (nylon monomer); ...
CYDONIA OBLONGA LEAF EXTRACT
Good
Chemical family
Skin Conditioning
Corynanthe Yohimbe Bark Extract
Poor
Chemical family
Humectant, Skin Conditioning
Dioctyldodecyl Adipate
Excellent
Chemical family
Emollient / skin conditioning (branch...
Is Yohimbe Bark Extract in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Yohimbe Bark Extract in your formulation.