Is Xylene safe in cosmetics?
Xylene has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Xylene
INCI: XYLENE
Xylene (CAS 1330-20-7 (mixed isomers)) is a cosmetic cosmetic ingredient functioning as Solvent. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1330-20-7 (mixed isomers) →
Auto-generated CPSR Part A draft with source citations
Function
Solvent
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not listed as a permitted cosmetic ingredient; classified as industrial solvent; FDA considers it unsafe for cosmetic application
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Xylene.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
pregnancy_detail
{"pregnancy_safe": "avoid", "breastfeeding_safe": "avoid", "trimester_restriction": "all", "risk_category": "not-rated", "reason": "Nervous system toxicant; inhalation risk", "alternative_ingredient": "7-free nail polish", "source": "toxicology literature"}
Expert Verdict
Expert safety assessment and concern-level summary for Xylene.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Xylene by CAS number or substance name.
Studies
12
Lowest NOAEL
75 mg/kg bw/day
Highest NOAEL
300 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Xylene allowed in the EU?
Xylene EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Xylene do in cosmetics?
Xylene functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 1330-20-7 (mixed isomers).
Compliance Tools
Check Xylene compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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