Veratraldehyde

Also known as: 3,4-Dimethoxybenzaldehyde, BRN 0473899, EINECS 204-373-2, FEMA No. 3109, Protocatechuecaldehyde dimethyl ether (+5 more)

INCI: VERATRALDEHYDE

Veratraldehyde (CAS 120-14-9) is a cosmetic cosmetic ingredient functioning as Perfuming (fragrance ingredient). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 120-14-9 →

Auto-generated CPSR Part A draft with source citations
Function
Perfuming (fragrance ingredient)
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C9H10O3
MW
166.17 g/mol
EC Number
204-373-2
PubChem CID
8419
IUPAC Name
3,4-dimethoxybenzaldehyde
InChIKey
WJUFSDZVCOTFON-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted; FDA 21 CFR 172.515 (food flavoring — GRAS); permitted in cosmetics

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Veratraldehyde.

Calculate MoS for your specific formulation with the MoS Calculator.

HRIPT Human Patch Test Studies

1 human repeat insult patch test aggregated from dermatological literature.

Test Type N Sensitized Dose µg/cm² NESIL µg/cm² Potency
HMT - 0 9720 - -

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Regulatory (6)
JECFA Number
877
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
METHYL VANILLIN | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
VERATRALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
VERATRIC ALDEHYDE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
VANILLIN METHYL ETHER | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/84 | FAS 48-JECFA 57/273
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Flavouring and nutrient Fragrance No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List FDA Substances Added to Food (EAFUS) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Veratraldehyde.

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Known Synonyms

3,4-Dimethoxybenzaldehyde BRN 0473899 EINECS 204-373-2 FEMA No. 3109 Protocatechuecaldehyde dimethyl ether p-Veratric aldehyde UNII-UI88P68JZD EC No.: 204-373-2 204-373-2 VERATRUM

Chemical Function

Fragrance No specific technical function Flavouring and nutrient

Regulatory Lists

Australia; Food and drug - smoking-related products IFRA Transparency Europe food_additive; Substances Added to Food (formerly EAFUS) (2/2019) consumer_product

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
3,4-DIMETHOXYBENZALDEHYDE
ChEMBL ID
CHEMBL1088937
View full pharmaceutical profile →

Frequently Asked Questions

Is Veratraldehyde safe in cosmetics?

Veratraldehyde has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Veratraldehyde allowed in the EU?

Veratraldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Veratraldehyde do in cosmetics?

Veratraldehyde functions as: Perfuming (fragrance ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 120-14-9.

Is Veratraldehyde used outside cosmetics?

Veratraldehyde also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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Excellent Same category
Fragrance
Acetoin
Excellent Same category
Skin conditioning, fragrance
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Benzyl Benzoate
Moderate Chemical family
fragrance; solvent; anti-parasitic
Benzyl Isoeugenol
Moderate Chemical family
Perfuming (fragrance ingredient)
Chlorophene
Poor Chemical family
Preservative / antimicrobial

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