Is Tris-Biphenyl Triazine safe in cosmetics?
Tris-Biphenyl Triazine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Tris-Biphenyl Triazine
Also known as: UNII-FQK9A410YB, 1,3,5-Triazine, 2,4,6-tris((1,1'-biphenyl)-4-yl)-, 2,4,6-Tris(p-biphenylyl)-s-triazine, S-Triazine, 2,4,6-tri-4-biphenylyl-, Tinosorb A2B
INCI: TRIS-BIPHENYL TRIAZINE / TRIS-BIPHENYL TRIAZINE (NANO)
Tris-Biphenyl Triazine (CAS 31274-51-8) is a cosmetic cosmetic ingredient functioning as UV Filter – most efficient UVB + UVA2 (290–340 nm) filter known; highly. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted, max 10%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 31274-51-8 →
Auto-generated CPSR Part A draft with source citations
Function
UV Filter – most efficient UVB + UVA2 (290–340 nm) filter known; highly photostable
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,4,6-tris(4-phenylphenyl)-1,3,5-triazine
InChIKey
CENPSTJGQOQKKW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
10%
US US Status
permitted
US Notes
NOT approved – not on FDA OTC sunscreen monograph; not permitted in US market
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tris-Biphenyl Triazine.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Tris-Biphenyl Triazine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Tris-Biphenyl Triazine across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex VI — Permitted UV Filters
Max: 10%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (VI - UV Filters)
Max: 0.1.
JPKR Japan/Korea Cosmetics
Korea (Restricted): max 10.0
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.1
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_uv_filter | 10 | All cosmetics (no spray) |
| BR | permitted_uv_filter | 10 | Sunscreen products; nanoform: primary particle >80nm, purity ≥98%, uncoated |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
UV stabilizer
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Tris-Biphenyl Triazine.
Regulatory Flags
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Tris-Biphenyl Triazine by CAS number or substance name.
Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
UNII-FQK9A410YB
1,3,5-Triazine, 2,4,6-tris((1,1'-biphenyl)-4-yl)-
2,4,6-Tris(p-biphenylyl)-s-triazine
S-Triazine, 2,4,6-tri-4-biphenylyl-
Tinosorb A2B
Chemical Function
UV stabilizer
Regulatory Lists
Europe; Personal care
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the concentration of the chemical exceeds or is...
Frequently Asked Questions
Is Tris-Biphenyl Triazine allowed in the EU?
Tris-Biphenyl Triazine EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.
What does Tris-Biphenyl Triazine do in cosmetics?
Tris-Biphenyl Triazine functions as: UV Filter – most efficient UVB + UVA2 (290–340 nm) filter known; highly photostable. It is classified as a cosmetic ingredient in our database. CAS number: 31274-51-8.
What is the NOAEL for Tris-Biphenyl Triazine?
The NOAEL (No Observed Adverse Effect Level) for Tris-Biphenyl Triazine is =1000 mg/kg bw/day based on a developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Tris-Biphenyl Triazine used outside cosmetics?
Tris-Biphenyl Triazine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Tris-Biphenyl Triazine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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