Is Benzophenone-5 safe in cosmetics?
Benzophenone-5 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Benzophenone-5
Also known as: Cyasorb UV 284, Uvistat 112, UNII-853Z42ZYAS
INCI: BENZOPHENONE-5
Benzophenone-5 (CAS 6628-37-1) is a cosmetic cosmetic ingredient functioning as UV filter, UV absorber, light stabilizer. EU Regulation 1223/2009 status: permitted, max 5%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 6628-37-1 →
Auto-generated CPSR Part A draft with source citations
Function
UV filter, UV absorber, light stabilizer
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
EU Max Conc.
5%
US US Status
permitted
US Notes
Not listed as OTC sunscreen active (BP-4 is, but BP-5 is not); CIR concluded safe (2021)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Benzophenone-5.
Calculate MoS for your specific formulation with the MoS Calculator.
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Suspected
Evidence: Limited
(2019)
Health effects: Yes
Affected pathways: Estrogenic
Regulatory framework: Cosmetics
Source list: II
Cosmetic-Specific Mechanism
Category: UV filter
Receptor targets: ERα, ERβ, AR
LOEC: 1 µM
EU status: restricted (max 5%, SCCS/1679/25 safe read-across BP-4)
agonist (ERα, ERβ); antagonist (AR)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_uv_filter | 5 | All cosmetics |
| IN | permitted_uv_filter | 5.0 | sunscreen and other cosmetic products |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
sunscreen_uv
{"cas_number": "6628-37-1", "uv_filter_type": "organic_broad_spectrum", "chemical_class": "benzophenone", "absorption_spectrum_nm_range": "280-340", "peak_absorption_wavelength_nm": "287", "molar_extinction_coefficient": "16800", "critical_wavelength_nm": "335", "UVA_PF": "3-5", "SPF_contribution_per_percent": "5.2", "photostability_rating": "photostable", "photodegradation_half_life_hours": ">10"…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
UV stabilizer
Expert Verdict
Expert safety assessment and concern-level summary for Benzophenone-5.
Known Synonyms
Cyasorb UV 284
Uvistat 112
UNII-853Z42ZYAS
Chemical Function
UV stabilizer
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Benzophenone-5 allowed in the EU?
Benzophenone-5 EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzophenone-5 do in cosmetics?
Benzophenone-5 functions as: UV filter, UV absorber, light stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 6628-37-1.
Compliance Tools
Check Benzophenone-5 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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