Is Trimethoxycaprylylsilane safe in cosmetics?
Trimethoxycaprylylsilane has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Trimethoxycaprylylsilane
INCI: TRIMETHOXYCAPRYLYLSILANE
Trimethoxycaprylylsilane (CAS 3069-40-7) is a cosmetic cosmetic ingredient functioning as Surface modifier, binder, skin conditioning (hydrophobic pigment/UV filter. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3069-40-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Trimethoxycaprylylsilane is classified GHS Danger (H315, H331, H332) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Surface modifier, binder, skin conditioning (hydrophobic pigment/UV filter surface treatment)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
trimethoxy(octyl)silane
InChIKey
NMEPHPOFYLLFTK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel concluded safe in cosmetics in present practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trimethoxycaprylylsilane.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Trimethoxycaprylylsilane across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
silicone
{"cas_number": "3069-42-9", "silicone_class": "organosilane", "molecular_weight_Da": "234.0", "viscosity_cSt": "liquid", "volatility": "non_volatile", "evaporation_rate_relative_to_D5": "0.06", "refractive_index": "1.421", "specific_gravity": "0.895", "flash_point_C": "72.0", "surface_tension_mN_m": "23.2", "spreading_coefficient": "3.3", "film_forming_ability": "good", "skin_feel": "powdery", "sl…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter
Binder
Chemical reaction regulator
Dispersing agent
Humectant
Surface modifier
Expert Verdict
Expert safety assessment and concern-level summary for Trimethoxycaprylylsilane.
Chemical Function
Binder
Humectant
Surface modifier
Chemical reaction regulator
Adhesion/cohesion promoter
Dispersing agent
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Trimethoxycaprylylsilane allowed in the EU?
Trimethoxycaprylylsilane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trimethoxycaprylylsilane do in cosmetics?
Trimethoxycaprylylsilane functions as: Surface modifier, binder, skin conditioning (hydrophobic pigment/UV filter surface treatment). It is classified as a cosmetic ingredient in our database. CAS number: 3069-40-7.
Is Trimethoxycaprylylsilane used outside cosmetics?
Trimethoxycaprylylsilane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Trimethoxycaprylylsilane have different safety status in cosmetics vs industrial chemicals?
Trimethoxycaprylylsilane is classified GHS Danger (H315, H331, H332) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Trimethoxycaprylylsilane compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Benzylidene Camphor Sulfonic Acid
Excellent
Same category
UV filter (broadband UVB + UVA absorb...
Dioctylaminoethoxytriazine Aminopropyl Silsesquioxane Silicate
Excellent
Same category
Film forming agent that creates prote...
Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (MBBT)
Excellent
Same category
UV filter, light stabilizer
Triethoxycaprylylsilane
Excellent
Same category
Binder, Surface Modifier, Skin Condit...
Tris-Biphenyl Triazine
Excellent
Same category
UV Filter – most efficient UVB + UVA2...
Benzophenone-5
Good
Same category
UV filter, UV absorber, light stabilizer
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
Excellent
Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
Excellent
Similar safety
Antioxidant; tyrosinase inhibitor; me...
Hexyltrimethoxysilane
Moderate
Chemical family
Surface modifier / hair and skin cond...
Stearyl Triethoxysilane
Good
Chemical family
Binding (pigment surface treatment/co...
TRI (POLYGLYCERYL-3/LAURYL) HYDROGENATED TRILINOLEATE
Good
Browse nearby
Surfactant - Cleansing, Surfactant - ...
Is Trimethoxycaprylylsilane in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Trimethoxycaprylylsilane in your formulation.