Is Trimethyl-Pentylcyclopentanone safe in cosmetics?
Trimethyl-Pentylcyclopentanone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Trimethyl-Pentylcyclopentanone
Also known as: Cyclopentanone, 2,2,5-trimethyl-5-pentyl-, EINECS 265-779-3, 2-Pentyl-2,5,5-trimethylcyclopentanone
INCI: 2,2,5-TRIMETHYL-5-PENTYLCYCLOPENTANONE
Trimethyl-Pentylcyclopentanone (CAS 65443-14-3) is a cosmetic cosmetic ingredient functioning as Fragrance component; skin-conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 65443-14-3 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance component; skin-conditioning agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2,2,5-trimethyl-5-pentylcyclopentan-1-one
InChIKey
PUKWIVZFEZFVAT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as a cosmetic fragrance ingredient; no specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trimethyl-Pentylcyclopentanone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | - | 0 | 4960.01 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Trimethyl-Pentylcyclopentanone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Cyclopentanone, 2,2,5-trimethyl-5-pentyl-
EINECS 265-779-3
2-Pentyl-2,5,5-trimethylcyclopentanone
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Trimethyl-Pentylcyclopentanone allowed in the EU?
Trimethyl-Pentylcyclopentanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trimethyl-Pentylcyclopentanone do in cosmetics?
Trimethyl-Pentylcyclopentanone functions as: Fragrance component; skin-conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 65443-14-3.
Is Trimethyl-Pentylcyclopentanone used outside cosmetics?
Trimethyl-Pentylcyclopentanone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Trimethyl-Pentylcyclopentanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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