What is the NOAEL for 2,2,5-Trimethyl-5-pentylcyclopentan-1-one?
2,2,5-Trimethyl-5-pentylcyclopentan-1-one has 8 NOAEL studies in the database. The lowest reported value is BN3YZU63MN UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,2,5-Trimethyl-5-pentylcyclopentan-1-one
Also known as: Cyclopentanone, 2,2,5-trimethyl-5-pentyl-, EINECS 265-779-3, 2-Pentyl-2,5,5-trimethylcyclopentanone, 2,2,5-Trimethyl-5-pentylcyclopentanone
CAS 65443-14-3
2,2,5-Trimethyl-5-pentylcyclopentan-1-one (CAS 65443-14-3) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Trimethyl-Pentylcyclopentanone →
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
2,2,5-Trimethyl-5-pentylcyclopentan-1-one
CAS Number
65443-14-3
DTXSID
DTXSID9052341
Molecular Formula
C13H24O
InChI Key
PUKWIVZFEZFVAT-UHFFFAOYSA-N
Monoisotopic Mass
196.182715
Synonyms
Cyclopentanone, 2,2,5-trimethyl-5-pentyl-EINECS 265-779-32-Pentyl-2,5,5-trimethylcyclopentanone2,2,5-Trimethyl-5-pentylcyclopentanone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
30 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| BN3YZU63MN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BN3YZU63MN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BN3YZU63MN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BN3YZU63MN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4960 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =12000 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,2,5-trimethyl-5-pentylcyclopentan-1-one | 265-779-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 2,2,5-Trimethyl-5-pentylcyclopentan-1-one?
2,2,5-Trimethyl-5-pentylcyclopentan-1-one appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 2,2,5-Trimethyl-5-pentylcyclopentan-1-one used in cosmetics?
Yes, 2,2,5-Trimethyl-5-pentylcyclopentan-1-one is also indexed as a cosmetic ingredient under the name Trimethyl-Pentylcyclopentanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,2,5-Trimethyl-5-pentylcyclopentan-1-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,2,5-Trimethyl-5-pentylcyclopentan-1-one used outside industrial chemicals?
2,2,5-Trimethyl-5-pentylcyclopentan-1-one also appears in cosmetics databases.