Is tert-Butyl Dimethyl Acetophenone safe in cosmetics?
tert-Butyl Dimethyl Acetophenone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
tert-Butyl Dimethyl Acetophenone
Also known as: Acetophenone, 4'-tert-butyl-2',6'-dimethyl-, Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]-, EINECS 218-037-8, NSC 15340, UNII-UN0DL0NR1U
INCI: TERT-BUTYL DIMETHYL ACETOPHENONE
tert-Butyl Dimethyl Acetophenone (CAS 2040-10-0) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2040-10-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
tert-Butyl Dimethyl Acetophenone is classified GHS Danger (H301, H312) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance / Perfuming agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1-(4-tert-butyl-2,6-dimethylphenyl)ethanone
InChIKey
JNHLHPMTMTYLCP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics as fragrance ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for tert-Butyl Dimethyl Acetophenone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for tert-Butyl Dimethyl Acetophenone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Acetophenone, 4'-tert-butyl-2',6'-dimethyl-
Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]-
EINECS 218-037-8
NSC 15340
UNII-UN0DL0NR1U
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3184068
Frequently Asked Questions
Is tert-Butyl Dimethyl Acetophenone allowed in the EU?
tert-Butyl Dimethyl Acetophenone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does tert-Butyl Dimethyl Acetophenone do in cosmetics?
tert-Butyl Dimethyl Acetophenone functions as: Fragrance / Perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 2040-10-0.
Is tert-Butyl Dimethyl Acetophenone used outside cosmetics?
tert-Butyl Dimethyl Acetophenone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does tert-Butyl Dimethyl Acetophenone have different safety status in cosmetics vs industrial chemicals?
tert-Butyl Dimethyl Acetophenone is classified GHS Danger (H301, H312) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check tert-Butyl Dimethyl Acetophenone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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