What is the NOAEL for 4'-tert-Butyl-2',6'-dimethylacetophenone?
4'-tert-Butyl-2',6'-dimethylacetophenone has 4 NOAEL studies in the database. The lowest reported value is UN0DL0NR1U UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
4'-tert-Butyl-2',6'-dimethylacetophenone
Also known as: Acetophenone, 4'-tert-butyl-2',6'-dimethyl-, Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]-, EINECS 218-037-8, NSC 15340, UNII-UN0DL0NR1U
CAS 2040-10-0
4'-tert-Butyl-2',6'-dimethylacetophenone (CAS 2040-10-0) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for tert-Butyl Dimethyl Acetophenone →
Cross-Vertical Regulatory Divergence
4'-tert-Butyl-2',6'-dimethylacetophenone is classified GHS Danger (H301, H312) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
4'-tert-Butyl-2',6'-dimethylacetophenone
CAS Number
2040-10-0
DTXSID
DTXSID9047120
Molecular Formula
C14H20O
InChI Key
JNHLHPMTMTYLCP-UHFFFAOYSA-N
Monoisotopic Mass
204.151415
Synonyms
Acetophenone, 4'-tert-butyl-2',6'-dimethyl-Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]-EINECS 218-037-8NSC 15340UNII-UN0DL0NR1U
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| UN0DL0NR1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UN0DL0NR1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UN0DL0NR1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| UN0DL0NR1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3184068
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 4'-tert-Butyl-2',6'-dimethylacetophenone?
4'-tert-Butyl-2',6'-dimethylacetophenone appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 4'-tert-Butyl-2',6'-dimethylacetophenone used in cosmetics?
Yes, 4'-tert-Butyl-2',6'-dimethylacetophenone is also indexed as a cosmetic ingredient under the name tert-Butyl Dimethyl Acetophenone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4'-tert-Butyl-2',6'-dimethylacetophenone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 4'-tert-Butyl-2',6'-dimethylacetophenone have different safety status in cosmetics vs industrial chemicals?
4'-tert-Butyl-2',6'-dimethylacetophenone is classified GHS Danger (H301, H312) in the chemicals database but is allowed in EU cosmetics.
Is 4'-tert-Butyl-2',6'-dimethylacetophenone used outside industrial chemicals?
4'-tert-Butyl-2',6'-dimethylacetophenone also appears in cosmetics, pharmaceutical databases.