Is Sodium Dihydroxyethylglycinate safe in cosmetics?
Sodium Dihydroxyethylglycinate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Sodium Dihydroxyethylglycinate
Also known as: Glycine, N,N-bis(2-hydroxyethyl)-, sodium salt (1:1), Glycine, N,N-bis(2-hydroxyethyl)-, monosodium salt, Bis(hydroxyethyl)glycine sodium salt, Chel 185, Chelest G 50 (+13 more)
INCI: SODIUM DIHYDROXYETHYLGLYCINATE
Sodium Dihydroxyethylglycinate (CAS 139-41-3) is a cosmetic cosmetic ingredient functioning as Preservative (antimicrobial), Chelating Agent. EU Regulation 1223/2009 status: permitted, max 0.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 139-41-3 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative (antimicrobial), Chelating Agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
sodium 2-[bis(2-hydroxyethyl)amino]acetate
InChIKey
MFBDBXAVPLFMNJ-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.5%
US US Status
permitted
US Notes
Permitted for cosmetic use as preservative
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Dihydroxyethylglycinate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Dihydroxyethylglycinate.
Regulatory Flags
preservative
Known Synonyms
Glycine, N,N-bis(2-hydroxyethyl)-, sodium salt (1:1)
Glycine, N,N-bis(2-hydroxyethyl)-, monosodium salt
Bis(hydroxyethyl)glycine sodium salt
Chel 185
Chelest G 50
Dihydroxyethylglycine, sodium salt
Hampshire DEG
Monaquest IA
N,N-Bis(β-hydroxyethyl)glycine sodium salt
N,N-Bis-2-hydroxyethylaminoacetic acid sodium salt
N,N-Di(2-hydroxyethyl)glycine monosodium salt
Sodium N,N-bis(2-hydroxyethyl)aminoacetate
Sodium N,N-bis(β-hydroxyethyl)glycinate
Sodium N,N-di-2-hydroxyethylglycinate
Sodium bis(β-hydroxyethyl)glycinate
Sodium diethanolglycinate
Syntron D
EINECS 205-360-4
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Sodium Dihydroxyethylglycinate allowed in the EU?
Sodium Dihydroxyethylglycinate EU regulatory status: permitted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Dihydroxyethylglycinate do in cosmetics?
Sodium Dihydroxyethylglycinate functions as: Preservative (antimicrobial), Chelating Agent. It is classified as a cosmetic ingredient in our database. CAS number: 139-41-3.
Is Sodium Dihydroxyethylglycinate used outside cosmetics?
Sodium Dihydroxyethylglycinate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Dihydroxyethylglycinate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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