Is Rumex Occidentalis Extract safe in cosmetics?
Rumex Occidentalis Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Rumex Occidentalis Extract
Also known as: BRN 7155654, Optiray, Optiray 160, Optiray 240, Optiray 320 (+4 more)
INCI: RUMEX OCCIDENTALIS EXTRACT
Rumex Occidentalis Extract (CAS 87771-40-2) is a cosmetic cosmetic ingredient functioning as Skin Brightening. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 87771-40-2 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Brightening
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Rumex Occidentalis Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
3 property records from structured ingredient metadata.
depigmentation
{"cas_number": "not established", "ingredient_class": "tyrosinase_inhibitor", "primary_mechanism_of_action": "Emodin and physcion provide melanin synthesis inhibition", "secondary_mechanisms": "Variable", "molecular_target": "tyrosinase", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction_pct_clinica…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "7.0", "stable_ph_min": "4.5", "stable_ph_max": "7.5", "degrades_above_ph": "8.0", "degrades_below_ph": "4.0", "ph_dependent_function": "Tyrosinase inhibitor", "formulation_note": "Natural brightening agent", "source": "Formulation literature"}
skin_brightening
{"cas_number": "84787-62-8", "mechanism_of_action": "Tyrosinase inhibition; antioxidant", "melanogenesis_pathway_target": "Tyrosinase", "tyrosinase_inhibition_ic50_um": "~80-150", "tyrosinase_inhibition_vs_kojic_acid": "~1-2x weaker", "melanosome_transfer_inhibitor": "No", "melanin_oxidation_reducer": "Partial", "endothelin_pathway_blocker": "No", "alpha_msh_antagonist": "No", "clinical_efficacy_s…
Expert Verdict
Expert safety assessment and concern-level summary for Rumex Occidentalis Extract.
Known Synonyms
BRN 7155654
Optiray
Optiray 160
Optiray 240
Optiray 320
Optiray 350
Optiray 300
Ioversolum
UNII-N3RIB7X24K
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
Canada; consumer_product; Substances in Products - Canada (4/2014)
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
IOVERSOL
ChEMBL ID
CHEMBL1200614
Max Phase
4
Adverse Event Associations
240
Frequently Asked Questions
Is Rumex Occidentalis Extract allowed in the EU?
Rumex Occidentalis Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Rumex Occidentalis Extract do in cosmetics?
Rumex Occidentalis Extract functions as: Skin Brightening. It is classified as a cosmetic ingredient in our database. CAS number: 87771-40-2.
Is Rumex Occidentalis Extract used outside cosmetics?
Rumex Occidentalis Extract also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Rumex Occidentalis Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
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