Royal Jelly

INCI: ROYAL JELLY

Royal Jelly (CAS 8031-67-2) is a cosmetic cosmetic ingredient functioning as skin conditioning agents. EU Regulation 1223/2009 status: permitted, max 20%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 8031-67-2 →

Auto-generated CPSR Part A draft with source citations
Function
skin conditioning agents
Safety Rating
MODERATE

Regulatory Status

EU EU Status permitted
EU Max Conc. 20%
US US Status permitted
US Notes Permitted cosmetic ingredient under FD&C Act. Not FDA GRAS-classified. Not food GRAS-affirmed. CIR Expert Panel 2025: safe in cosmetics at present concentrations provided ingredient is free of pesticide residues and heavy metal contaminants (Pb ≤10 ppm, As ≤3 ppm, Hg ≤1 ppm).

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Royal Jelly.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

6 property records from structured ingredient metadata.

concentration
{"min_concentration_pct": "0.5", "max_concentration_pct": "3.0", "typical_concentration_pct": "1.5", "product_type": "Moisturizer", "function_at_concentration": "Nourishing", "source": "Supplier TDS"}
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "120", "estimated_cost_per_kg_usd_high": "220", "natural_premium_markup_pct": "160", "organic_certified_premium_pct": "280", "supply_chain_volatility": "high", "primary_source_region": "China/Taiwan", "synthetic_vs_natural_cost_ratio": "3.0", "bulk_discount_threshold_kg": "10", "seasonal_price_variation": "high", "commodity_or_specialty": "…
pediatric_safety
{"safe_for_newborn_0_6m": "caution", "safe_for_infant_6_12m": "caution", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "2.0", "adult_max_concentration_pct": "5.0", "pediatric_dermal_absorption_factor": "normal", "immature_skin_barrier_risk": "low", "oral_ingestion_risk": "low", "diaper_area_safe": "yes", "pediatric_…
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "acceptable", "sensitive_skin": "caution", "combination_skin": "acceptable", "normal_skin": "acceptable", "acne_prone": "acceptable", "rosacea": "caution", "eczema": "caution", "hyperpigmentation": "acceptable", "aging_mature": "acceptable", "dehydrated": "acceptable", "skin_benefit_primary": "anti-aging", "skin_benefit_secondary": "nourishing", "mechanism_o…
supply_chain
{"primary_producing_countries": "China, Japan, Taiwan", "secondary_producing_countries": "South Korea, Thailand", "raw_material_origin": "animal", "agricultural_crop_or_wild_harvested": "bee_product", "cultivation_climate_required": "beekeeping", "harvest_season": "year_round", "annual_global_production_tonnes": "4200", "market_share_top_producer_pct": "78", "supply_chain_length": "2_intermediarie…
uv_stability
{"uv_stable": "partially", "uv_degradation_rate": "moderate", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "15", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_un…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Royal Jelly.

Regulatory Flags

skin-conditioning allergen-risk bee-derived natural-origin no-concentration-limit anaphylaxis-risk cross-reactive-allergen no-mos-calculated

Chemical Function

Softener and conditioner

Regulatory Lists

Canada; pharmaceutical

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
8
View full pharmaceutical profile →

Frequently Asked Questions

Is Royal Jelly safe in cosmetics?

Royal Jelly has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.

Is Royal Jelly allowed in the EU?

Royal Jelly EU regulatory status: permitted. Maximum allowed concentration: 20%. This is based on EU Regulation 1223/2009 and its amendments.

What does Royal Jelly do in cosmetics?

Royal Jelly functions as: skin conditioning agents. It is classified as a cosmetic ingredient in our database. CAS number: 8031-67-2.

Is Royal Jelly used outside cosmetics?

Royal Jelly also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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