Is PVP-Iodine safe in cosmetics?
PVP-Iodine has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
PVP-Iodine
Also known as: Iodine, compd. with 1-ethenyl-2-pyrrolidinone homopolymer, Iodine, compd. with 1-vinyl-2-pyrrolidinone polymers, Argentyne, Braunosan H, Bridine (+15 more)
INCI: PVP-IODINE (POVIDONE-IODINE) [^1_18]
PVP-Iodine (CAS 25655-41-8) is a cosmetic cosmetic ingredient functioning as Antimicrobial, antiseptic (primarily pharmaceutical, not cosmetic) [^1_18]. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 25655-41-8 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, antiseptic (primarily pharmaceutical, not cosmetic) [^1_18]
Safety Rating
POOR
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA-approved OTC antiseptic drug; not a standard cosmetic ingredient [^1_18][^1_20]
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PVP-Iodine.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for PVP-Iodine.
Known Synonyms
Iodine, compd. with 1-ethenyl-2-pyrrolidinone homopolymer
Iodine, compd. with 1-vinyl-2-pyrrolidinone polymers
Argentyne
Braunosan H
Bridine
Disadine D.P.
Efo-dine
Iodine-polyvinylpyrrolidone complex
Iodopoly(vinyl pyrrolidinone)
Poly(vinylpyrrolidone) - iodine complex
Povidone iodine
Povidone-lodine
PVP iodine
Ultradine
1-Vinyl-2-pyrrolidinone polymer, compd. with iodine
E-Z Prep
E-Z Prep 220
E-Z Scrub 201
E-Z Scrub 241
UNII-85H0HZU99M
Chemical Function
Biocide
Regulatory Lists
active_ingredient; Europe; Pesticides
Europe; pharmaceutical
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
povidone-iodine
ChEMBL ID
CHEMBL1201724
Adverse Event Associations
1943
Frequently Asked Questions
Is PVP-Iodine allowed in the EU?
PVP-Iodine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PVP-Iodine do in cosmetics?
PVP-Iodine functions as: Antimicrobial, antiseptic (primarily pharmaceutical, not cosmetic) [^1_18]. It is classified as a cosmetic ingredient in our database. CAS number: 25655-41-8.
Is PVP-Iodine used outside cosmetics?
PVP-Iodine also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check PVP-Iodine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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