Is Protodioscin safe in cosmetics?
Protodioscin has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Protodioscin
Also known as: (3β,22R,25R)-26-(β-D-Glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside, beta-D-glucopyranoside, (3beta,22alpha,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl o-6-deoxy-alpha-l-mannopyranosyl-(1->2)-o-[6-deoxy-alpha-l-mannopyranosyl-(1->4)]-
INCI: PROTODIOSCIN
Protodioscin (CAS 55056-80-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning (steroidal saponin from *Tribulus terrestris*). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 55056-80-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning (steroidal saponin from *Tribulus terrestris*)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
(2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[[(1S,2S,4S,6R,7S,8R,9S,12S,13R,16S)-6-hydroxy-7,9,13-trimethyl-6-[(3R)-3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
InChIKey
LVTJOONKWUXEFR-UEZXSUPNSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically listed for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Protodioscin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Protodioscin.
Known Synonyms
(3β,22R,25R)-26-(β-D-Glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside
beta-D-glucopyranoside, (3beta,22alpha,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl o-6-deoxy-alpha-l-mannopyranosyl-(1->2)-o-[6-deoxy-alpha-l-mannopyranosyl-(1->4)]-
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL4782480
Frequently Asked Questions
Is Protodioscin allowed in the EU?
Protodioscin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Protodioscin do in cosmetics?
Protodioscin functions as: Skin conditioning (steroidal saponin from *Tribulus terrestris*). It is classified as a cosmetic ingredient in our database. CAS number: 55056-80-9.
Is Protodioscin used outside cosmetics?
Protodioscin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Perfuming
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