Is Propyl Butyrate safe in cosmetics?
Propyl Butyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Propyl Butyrate
Also known as: 4-02-00-00788, BRN 1745552, EINECS 203-320-0, FEMA No. 2934, Propyl butanoate (+11 more)
INCI: PROPYL BUTYRATE
Propyl Butyrate (CAS 105-66-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, Solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 105-66-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient, Solvent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
propyl butanoate
InChIKey
HUAZGNHGCJGYNP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FEMA GRAS (No. 2934) as flavoring agent; CIR assessed safe as part of alkyl esters group
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Propyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
150
Source: WHO/JECFA
JECFA Evaluation
PROPYL BUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Propyl Butyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
4-02-00-00788
BRN 1745552
EINECS 203-320-0
FEMA No. 2934
Propyl butanoate
1-Propyl butyrate
Propylester kyseliny maselne
UNII-CW590750SQ
Butyric acid, propyl ester
N-Butyric acid N-propyl ester
N-Propyl N-butyrate
N-Propyl butyrate
N-Propyl-N-butanoate
Propyl N-butyrate
Propyl bytanoate
Propyl ester of butanoic acid
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Propyl Butyrate allowed in the EU?
Propyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Propyl Butyrate do in cosmetics?
Propyl Butyrate functions as: Fragrance ingredient, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 105-66-8.
Is Propyl Butyrate used outside cosmetics?
Propyl Butyrate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Propyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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