Is Polyquaternium-44 safe in cosmetics?
Polyquaternium-44 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Polyquaternium-44
Also known as: Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propen-1-yl)oxy]-, chloride (1:1), polymer with 2-propenamide, Polyquaternium-32, Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chloride, polymer with 2-propenamide, 2-Propenamide, polymer with N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]ethanaminium chloride, (2-Methacryloyloxyethyl)trimethylammonium chlorideacrylamide copolymer (+15 more)
INCI: POLYQUATERNIUM-44
Polyquaternium-44 (CAS 35429-19-7) is a cosmetic cosmetic ingredient functioning as conditioning agent, anti-static, film-forming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 35429-19-7 →
Auto-generated CPSR Part A draft with source citations
Function
conditioning agent, anti-static, film-forming
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel: safe as used; large molecular size and high polarity make dermal absorption unlikely
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyquaternium-44.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
5 property records from structured ingredient metadata.
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "365+", "bioaccumulative": "yes", "aquatic_toxicity_level": "moderate", "coral_reef_safe": "unknown", "marine_toxicity": "moderate toxicity", "freshwater_toxicity": "persistent polymer", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental":…
hair_care
{"hair_function": "styling", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "keratin_b…
hair_conditioning
{"cas_number": "150595-70-1", "ingredient_class": "cationic_conditioner", "chemical_type": "polyquaternium", "charge_density_meq_g": "1.8", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "yes", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic_film_forming", "hair_penetration": "surface_only", "molecular_weight_effect_on_penetration": "medium_MW_film"…
polymer
{"cas_number": "136955-29-2", "ingredient_class": "film_former/conditioning", "polymer_type": "synthetic_copolymer", "chemical_backbone": "vinyl", "molecular_weight_Da_range": "250000-2000000", "ionic_character": "cationic", "charge_density_meq_g": "2.0-3.5", "pH_viscosity_sensitivity": "moderate", "salt_tolerance": "moderate", "electrolyte_effect_on_viscosity": "moderate", "temperature_viscosity_…
rheology
{"cas_number": "83825-11-4", "rheology_modifier_type": "Synthetic Polymer - Cationic", "thickening_mechanism": "Hydrophobic association with surfactant micelles", "viscosity_increase_factor": "15000-60000x", "brookfield_viscosity_typical_cps": "2200-11000", "shear_thinning_behavior": "Excellent", "thixotropic": "Yes", "yield_stress_pa": "18-45", "flow_curve_type": "Pseudoplastic", "optimal_ph_rang…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Film former
Expert Verdict
Expert safety assessment and concern-level summary for Polyquaternium-44.
Regulatory Flags
cir-approved
conditioning-polymer
anti-static
substantive
coacervation
film-forming
eu_children_restricted
Known Synonyms
Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propen-1-yl)oxy]-, chloride (1:1), polymer with 2-propenamide
Polyquaternium-32
Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]-, chloride, polymer with 2-propenamide
2-Propenamide, polymer with N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-propenyl)oxy]ethanaminium chloride
(2-Methacryloyloxyethyl)trimethylammonium chlorideacrylamide copolymer
(Methacryloxyethyl)trimethylammonium chloride-acrylamide polymer
Acrylamide dimethylaminoethyl methacrylate methyl chloride quaternized salt polymer
Acrylamide-(2-methacryloyloxyethyl)trimethylammonium chloride copolymer
Acrylamide-2-(dimethylamino)ethyl methacrylate methyl chloride copolymer
Acrylamide-2-(trimethylammonio)ethyl methacrylate chloride copolymer
Acrylamide-2- methacryloxyethyltrimethylammonium chloride copolymer
Acrylamide-N,N-dimethylaminoethyl methacrylate methyl chloride salt copolymer
Acrylamide-[2-(methacryloyloxy)ethyl]trimethylammonium chloride polymer
Acrylamide-dimethylaminoethyl methacrylate methyl chloride copolymer
Nalco 7541
Sanfloc C 509P
Zetag 7888
Acrylamide, chloride salt of trimethylammonioethyl methacrylate copolymer
Acrylamide, copolymer with methacrylic acid, 2-(trimethylammonio)ethyl ester, chloride
Acrylamide, ((methacryloyloxy)ethyl)trimethylammonium chloride copolymer
Chemical Function
Film former
Anti-static agent
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Polyquaternium-44 allowed in the EU?
Polyquaternium-44 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyquaternium-44 do in cosmetics?
Polyquaternium-44 functions as: conditioning agent, anti-static, film-forming. It is classified as a cosmetic ingredient in our database. CAS number: 35429-19-7.
Compliance Tools
Check Polyquaternium-44 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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