Is Piracetam safe in cosmetics?
Piracetam has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Piracetam
Also known as: 1-Pyrrolidineacetamide, 2-oxo-, 2-Oxo-1-Pyrrolidineacetamide, 5-21-06-00360, 1-Acetamido-2-pyrrolidinone, BRN 1526393 (+9 more)
INCI: PIRACETAM
Piracetam (CAS 7491-74-9) is a cosmetic cosmetic ingredient functioning as Pharmaceutical nootropic. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7491-74-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Piracetam is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Pharmaceutical nootropic
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
2-(2-oxopyrrolidin-1-yl)acetamide
InChIKey
GMZVRMREEHBGGF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not FDA-approved as drug or cosmetic ingredient; classified as unapproved drug if therapeutic claims are made
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Piracetam.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Piracetam.
Known Synonyms
1-Pyrrolidineacetamide, 2-oxo-
2-Oxo-1-Pyrrolidineacetamide
5-21-06-00360
1-Acetamido-2-pyrrolidinone
BRN 1526393
Ciclofalina
EINECS 231-312-7
2-Ketopyrrolidine-1-ylacetamide
2-Oxo-pyrrolidine acetamide
2-Oxo-pyrrolidin-1-ylacetamide
Naofukang
Piracetamum
UNII-ZH516LNZ10
Breinox
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
pharmaceutical
Canada; pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PIRACETAM
ChEMBL ID
CHEMBL36715
Max Phase
3
Adverse Event Associations
130
Frequently Asked Questions
Is Piracetam allowed in the EU?
Piracetam EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Piracetam do in cosmetics?
Piracetam functions as: Pharmaceutical nootropic. It is classified as a cosmetic ingredient in our database. CAS number: 7491-74-9.
Is Piracetam used outside cosmetics?
Piracetam also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Piracetam have different safety status in cosmetics vs industrial chemicals?
Piracetam is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check Piracetam compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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