What is the NOAEL for 2-Oxo-1-Pyrrolidineacetamide?
2-Oxo-1-Pyrrolidineacetamide has 5 NOAEL studies in the database. The lowest reported value is ZH516LNZ10 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Oxo-1-Pyrrolidineacetamide
Also known as: 1-Pyrrolidineacetamide, 2-oxo-, Piracetam, 5-21-06-00360, 1-Acetamido-2-pyrrolidinone, BRN 1526393 (+9 more)
CAS 7491-74-9
2-Oxo-1-Pyrrolidineacetamide (CAS 7491-74-9) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
2-Oxo-1-Pyrrolidineacetamide is prohibited in EU cosmetics but has active industrial GHS classifications.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
2-Oxo-1-Pyrrolidineacetamide
CAS Number
7491-74-9
DTXSID
DTXSID5044491
Molecular Formula
C6H10N2O2
InChI Key
GMZVRMREEHBGGF-UHFFFAOYSA-N
Monoisotopic Mass
142.074228
Synonyms
1-Pyrrolidineacetamide, 2-oxo-Piracetam5-21-06-003601-Acetamido-2-pyrrolidinoneBRN 1526393CiclofalinaEINECS 231-312-72-Ketopyrrolidine-1-ylacetamide2-Oxo-pyrrolidine acetamide2-Oxo-pyrrolidin-1-ylacetamideNaofukangPiracetamum
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| ZH516LNZ10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZH516LNZ10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZH516LNZ10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZH516LNZ10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =400 | mg/kg bw/day | NOEL | injection | Rat | ToxValDB_ECOTOX |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PIRACETAM
ChEMBL Phase
3
Adverse Events
130
Bioactivity
3
Frequently Asked Questions
What regulatory lists include 2-Oxo-1-Pyrrolidineacetamide?
2-Oxo-1-Pyrrolidineacetamide appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is 2-Oxo-1-Pyrrolidineacetamide used in cosmetics?
Yes, 2-Oxo-1-Pyrrolidineacetamide is also indexed as a cosmetic ingredient under the name Piracetam. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Oxo-1-Pyrrolidineacetamide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Oxo-1-Pyrrolidineacetamide have different safety status in cosmetics vs industrial chemicals?
2-Oxo-1-Pyrrolidineacetamide is prohibited in EU cosmetics but has active industrial GHS classifications.
Is 2-Oxo-1-Pyrrolidineacetamide used outside industrial chemicals?
2-Oxo-1-Pyrrolidineacetamide also appears in cosmetics, pharmaceutical databases.