Is PHMB Cosmetic safe in cosmetics?
PHMB Cosmetic has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
PHMB Cosmetic
Also known as: Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
INCI: POLYAMINOPROPYL BIGUANIDE
PHMB Cosmetic (CAS 133029-32-0) is a cosmetic preservative functioning as Preservative. EU Regulation 1223/2009 status: restricted, max 0.3%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 133029-32-0 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.3%
US US Status
permitted
US Notes
No specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PHMB Cosmetic.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for PHMB Cosmetic based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
formaldehyde-releaser-group
Reaction Type
contact-dermatitis
Source: ESSCA 2019/20; IVDK; FDA
Additional Ingredient Properties
2 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "preservative", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "IVDK; SCCS"}
deodorant
{"cas_number": "32289-58-0", "ingredient_class": "antimicrobial_deodorant", "mechanism_of_action": "bacterial_growth_inhibition", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "24", "odor_reduction_pct": "60-80", "bacteriostatic": "yes", "bactericidal": "yes", "target_bacteria": "broad_spectrum", "microbiome_impact": "broad", "axillary_microbiome_effect": "varies …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antiperspirant
Biocide
Preservative
Expert Verdict
Expert safety assessment and concern-level summary for PHMB Cosmetic.
Regulatory Flags
EU Restricted
CMR
Allergen
Known Synonyms
Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
Chemical Function
Preservative
Biocide
Antiperspirant
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
Canada; Personal care; Substances in PCP - Canada (4/2014)
Canada; pharmaceutical
Frequently Asked Questions
Is PHMB Cosmetic allowed in the EU?
PHMB Cosmetic EU regulatory status: restricted. Maximum allowed concentration: 0.3%. This is based on EU Regulation 1223/2009 and its amendments.
What does PHMB Cosmetic do in cosmetics?
PHMB Cosmetic functions as: Preservative. It is classified as a Preservative in our database. CAS number: 133029-32-0.
Compliance Tools
Check PHMB Cosmetic compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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