Is Glyceryl Caprylate safe in cosmetics?
Glyceryl Caprylate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Preservative
Glyceryl Caprylate
Also known as: Monocaprylin, EINECS 247-668-1, Sunsoft 700P, Sunsoft 700p2, Octanoin, mono- (+5 more)
INCI: GLYCERYL CAPRYLATE
Glyceryl Caprylate (CAS 26402-26-6) is a cosmetic preservative functioning as Antimicrobial agent; emollient; preservative booster; natural preservation. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 26402-26-6 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial agent; emollient; preservative booster; natural preservation system component
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,3-dihydroxypropyl octanoate
InChIKey
GHBFNMLVSPCDGN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted without specific concentration caps. Used as natural antimicrobial ingredient. COSMOS/ECOCERT certified natural origin — important for eco-certified formulations. FDA considers safe as multifunctional cosmetic ingredient.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Caprylate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
9 property records from structured ingredient metadata.
acne
{"cas_number": "26402-26-6", "anti_acne_mechanism": "antibacterial", "comedogenicity_rating_0_to_5": "0-1", "acne_type_efficacy": "inflammatory", "p_acnes_mic_ug_per_ml": ">500", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "Max 1-2%", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne":…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,combination,normal,acne-prone", "acne_safe": "yes", "source": "Natural emulsifier"}
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
emulsifier
{"cas_number": "26402-26-6", "ingredient_class": "O/W_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "6.5", "HLB_required_for_oil_phase": "6-8", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "2-5", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "foam_stability": "low", "liquid_crystal_formation"…
emulsion_hlb
{"hlb_value": "5.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.48-0.68", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "sorbitan_laurate", "optimal_oil_phase_pct": "48-75", "optimal_water_phase_pct": "25-52", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "4.5-10.5", "viscosity_building_…
microbiome_impact
{"microbiome_effect": "mixed", "prebiotic": "no", "probiotic_compatible": "yes", "antimicrobial_spectrum": "selective", "preservative_effect_on_microbiome": "Emollient with antimicrobial properties; selective pathogen inhibition", "skin_flora_disruption": "mild", "gut_microbiome_risk": "low", "microbiome_recovery_time": "3-5 days", "selective_antimicrobial": "yes", "beneficial_bacteria_support": "…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "9.0", "stable_ph_min": "3.5", "stable_ph_max": "10.0", "ph_dependent_function": "Emulsifier and preservative booster", "formulation_note": "Multifunctional", "source": "Formulation literature"}
preservative
{"preservative_class": "Glyceryl ester", "antimicrobial_spectrum_bacteria_gp": "Moderate", "antimicrobial_spectrum_bacteria_gn": "Good", "antimicrobial_spectrum_yeast": "Yes", "antimicrobial_spectrum_mold": "Yes", "mic_staph_aureus_ppm": "2000", "mic_e_coli_ppm": "1800", "mic_pseudomonas_ppm": "2500", "mic_candida_albicans_ppm": "2000", "mic_aspergillus_niger_ppm": "3000", "challenge_test_pass_con…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Emulsifier
Preservative
Softener and conditioner
Surfactant (surface active agent)
Regulatory List Membership (2)
EU Regulated in Personal Care
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Glyceryl Caprylate.
Regulatory Flags
cosmos-approved
ecocert-approved
natural-derived
antimicrobial
emollient
synergizes-magnolia
synergizes-caprylhydroxamic-acid
hurdle-technology
not-annex-v
medium-chain-fatty-acid
epa_safer_alternative
Known Synonyms
Monocaprylin
EINECS 247-668-1
Sunsoft 700P
Sunsoft 700p2
Octanoin, mono-
Caprylic acid monoglyceride
Glycerin monocaprylate
Capmul MCM-C 8
Glycerol monocaprylate
Imwitor 308
Chemical Function
Softener and conditioner
Emulsifier
Biocide
Regulatory Lists
Europe; Personal care
Canada; Personal care; Substances in PCP - Canada (4/2014)
Europe; Personal care
Europe; Personal care
Europe; Personal care
SCIL (9/2019)
inert_ingredient; Pesticides
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Glyceryl Caprylate allowed in the EU?
Glyceryl Caprylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glyceryl Caprylate do in cosmetics?
Glyceryl Caprylate functions as: Antimicrobial agent; emollient; preservative booster; natural preservation system component. It is classified as a Preservative in our database. CAS number: 26402-26-6.
Is Glyceryl Caprylate used outside cosmetics?
Glyceryl Caprylate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glyceryl Caprylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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