What is the NOAEL for Polyaminopropyl biguanide?
Polyaminopropyl biguanide has 4 NOAEL studies in the database. The lowest reported value is DT9D8Z79ET UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Polyaminopropyl biguanide
Also known as: Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
CAS 133029-32-0
Polyaminopropyl biguanide (CAS 133029-32-0) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
4 fields
Name
Polyaminopropyl biguanide
CAS Number
133029-32-0
DTXSID
DTXSID601018305
Synonyms
Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
PreservativeBiocideAntiperspirant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| DT9D8Z79ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DT9D8Z79ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DT9D8Z79ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DT9D8Z79ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.3%
Category
preservative
Frequently Asked Questions
What regulatory lists include Polyaminopropyl biguanide?
Polyaminopropyl biguanide appears on 3 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), Canada; Personal care; Substances in PCP - Canada (4/2014), Canada; pharmaceutical. Source: EPA CPDat.
Is Polyaminopropyl biguanide used in cosmetics?
Yes, Polyaminopropyl biguanide is also indexed as a cosmetic ingredient under the name PHMB Cosmetic. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polyaminopropyl biguanide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Polyaminopropyl biguanide used outside industrial chemicals?
Polyaminopropyl biguanide also appears in cosmetics databases.