Is Phenyl Trimethicone safe in cosmetics?
Phenyl Trimethicone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Phenyl Trimethicone
Also known as: EINECS 218-320-6, UNII-DR0K5NOJ4R
INCI: PHENYL TRIMETHICONE
Phenyl Trimethicone (CAS 2116-84-9) is a cosmetic emollient functioning as emollient, hair conditioning, optical enhancer, refractive-index modifier. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2116-84-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Phenyl Trimethicone is classified GHS Danger (H315, H319, H330, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
emollient, hair conditioning, optical enhancer, refractive-index modifier
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA restriction; not separately assessed by CIR but falls within general silicone polymer safety framework; widely used in hair gloss and anti-aging serums
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenyl Trimethicone.
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Phenyl Trimethicone, relevant to systemic exposure and MoS calculations.
Absorption %
0.1-0.5%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
296.6 Da
Log P
6.2
Systemic Absorption
minimal
Topical Bioavailability
0.05-0.2%
Safety Margin Factor
minimal
Source: CIR
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
10 property records from structured ingredient metadata.
baby_pediatric
{"cas_number": "2116-84-9", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "6", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Resin silicone, shine", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Non-absorbed polymer", "skin_surface_area_to_weight_rati…
comedogenicity_detail
{"comedogenicity_rating": "1", "irritancy_rating": "0", "skin_type_suitability": "all,combination,normal", "acne_safe": "yes", "source": "Phenyl silicone"}
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "5.0", "typical_concentration_pct": "3.0", "product_type": "Sunscreen", "function_at_concentration": "Water resistance", "source": "CIR Safety Assessment"}
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "20", "estimated_cost_per_kg_usd_high": "38", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Global", "bulk_discount_threshold_kg": "150", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Dimethicone, C…
deodorant
{"cas_number": "2116-84-9", "ingredient_class": "other", "mechanism_of_action": "other", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "0", "odor_reduction_pct": "0", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "astringency_level": "varie…
dermal_absorption
{"molecular_weight_da": "296.6", "log_p_value": "6.2", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0.1-0.5", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "yes", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0.05-0.2", "safety_margin_factor": "minimal", "source": "C…
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "1200+", "bioaccumulative": "yes", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "low toxicity", "freshwater_toxicity": "persistent", "soil_toxicity": "sediment accumulation", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_r…
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "9-10", "co_emulsifier_pairs": "cetyl_dimethicone_copolyol", "optimal_oil_phase_pct": "20-50", "optimal_water_phase_pct": "50-80", "droplet_size_range_um": "0.5-15", "creaming_resistance": "good", "coalescence_resistance": "good", "ostwald_ripening_resistance": "moderate", "freeze_thaw_stability": "good", "rheology_modifier_type": "…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive
Defoamer
Flow promoter
Humectant
Softener and conditioner
Surface modifier
Waterproofing agent
Wetting agent (non-aqueous)
Expert Verdict
Expert safety assessment and concern-level summary for Phenyl Trimethicone.
Regulatory Flags
non-volatile-silicone
high-molecular-weight
optical-enhancer
heat-protection
shine-booster
cosmos-prohibited
Known Synonyms
EINECS 218-320-6
UNII-DR0K5NOJ4R
Chemical Function
Softener and conditioner
Defoamer
Humectant
Anti-adhesive/cohesive
Flow promoter
Regulatory Lists
Canada; pharmaceutical
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Phenyl Trimethicone allowed in the EU?
Phenyl Trimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenyl Trimethicone do in cosmetics?
Phenyl Trimethicone functions as: emollient, hair conditioning, optical enhancer, refractive-index modifier. It is classified as a Emollient in our database. CAS number: 2116-84-9.
Is Phenyl Trimethicone used outside cosmetics?
Phenyl Trimethicone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Phenyl Trimethicone have different safety status in cosmetics vs industrial chemicals?
Phenyl Trimethicone is classified GHS Danger (H315, H319, H330, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Phenyl Trimethicone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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