Is Phenethyl Tiglate safe in cosmetics?
Phenethyl Tiglate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Phenethyl Tiglate
Also known as: 2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (2E)-, 2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (E)-, 2-Butenoic acid, 2-methyl-, phenethyl ester, Phenethyl 2-methylcrotonate, 1-06-00-00238 (+11 more)
INCI: PHENETHYL TIGLATE
Phenethyl Tiglate (CAS 55719-85-2) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 55719-85-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-phenylethyl (E)-2-methylbut-2-enoate
InChIKey
KVMWYGAYARXPOL-QDEBKDIKSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics as fragrance ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenethyl Tiglate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 3888 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
997
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-PHENYLETHYL TIGLATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/53 | FAS 50-JECFA 59/215
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
PHENETHYL TIGLATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/53 | FAS 50-JECFA 59/215
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Phenethyl Tiglate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (2E)-
2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (E)-
2-Butenoic acid, 2-methyl-, phenethyl ester
Phenethyl 2-methylcrotonate
1-06-00-00238
Benzylcarbinyl tiglate
BRN 2523411
EINECS 259-774-5
FEMA No. 2870
2-Phenylethyl trans-2,3-dimethylacrylate
2-Phenylethyl trans-2-methylbutenoate
2-Phenylethyl 2-methyl-2-butenoate, (E)-
Phenylethyl tiglate
2-Phenylethyl tiglate
Phenylethyl-alpha-methylbutenoate
UNII-121LO7146V
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3560718
Frequently Asked Questions
Is Phenethyl Tiglate allowed in the EU?
Phenethyl Tiglate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenethyl Tiglate do in cosmetics?
Phenethyl Tiglate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 55719-85-2.
Is Phenethyl Tiglate used outside cosmetics?
Phenethyl Tiglate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Phenethyl Tiglate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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