What is the NOAEL for Phenethyl 2-methylcrotonate?
Phenethyl 2-methylcrotonate has 7 NOAEL studies in the database. The lowest reported value is 121LO7146V UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Phenethyl 2-methylcrotonate
Also known as: 2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (2E)-, 2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (E)-, 2-Butenoic acid, 2-methyl-, phenethyl ester, 1-06-00-00238, Benzylcarbinyl tiglate (+11 more)
CAS 55719-85-2
Phenethyl 2-methylcrotonate (CAS 55719-85-2) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Dimethyl Phenethyl Butyrate →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Phenethyl 2-methylcrotonate
CAS Number
55719-85-2
DTXSID
DTXSID8047684
Molecular Formula
C13H16O2
InChI Key
KVMWYGAYARXPOL-QDEBKDIKSA-N
Monoisotopic Mass
204.11503
Synonyms
2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (2E)-2-Butenoic acid, 2-methyl-, 2-phenylethyl ester, (E)-2-Butenoic acid, 2-methyl-, phenethyl ester1-06-00-00238Benzylcarbinyl tiglateBRN 2523411EINECS 259-774-5FEMA No. 28702-Phenylethyl trans-2,3-dimethylacrylate2-Phenylethyl trans-2-methylbutenoate2-Phenylethyl 2-methyl-2-butenoate, (E)-Phenylethyl tiglate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 121LO7146V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 121LO7146V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 121LO7146V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 121LO7146V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3888 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3560718
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Phenethyl 2-methylcrotonate?
Phenethyl 2-methylcrotonate appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Phenethyl 2-methylcrotonate used in cosmetics?
Yes, Phenethyl 2-methylcrotonate is also indexed as a cosmetic ingredient under the name Dimethyl Phenethyl Butyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Phenethyl 2-methylcrotonate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Phenethyl 2-methylcrotonate used outside industrial chemicals?
Phenethyl 2-methylcrotonate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.