Is Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo safe in cosmetics?
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted.
Moderate
Active Ingredient
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo
INCI: PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo (CAS 883558-32-5) is a cosmetic active ingredient functioning as Skin conditioning, anti-aging signal peptide. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 883558-32-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-aging signal peptide
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2S,3R)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]butanoyl]amino]-3-hydroxybutanoic acid;bis(2,2,2-trifluoroacetic acid)
InChIKey
MCCUAUFXOWFEEM-LAUWSANRSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR Expert Panel reviewed Palmitoyl Oligopeptides as a group (including palmitoyl dipeptide ingredients) in their March 2013 meeting. Key findings from the broader palmitoyl peptide safety review indicate this ingredient is regulated as an OTC drug with specific use restrictions.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
peptide
{"cas_number": "1036207-61-0", "trade_name": "Syn-Tacks", "peptide_sequence_amino_acids": "Pal-Lys-Thr-Dab", "peptide_length_residues": "3", "molecular_weight_daltons": "643.8", "peptide_class": "signal", "mechanism_of_action": "Stimulates syndecan-1 and collagen IV at dermal-epidermal junction", "target_protein_or_receptor": "Syndecan-1/DEJ proteins", "biomimetic_of": "laminin", "collagen_stimula…
Expert Verdict
Expert safety assessment and concern-level summary for Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo.
Frequently Asked Questions
Is Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo allowed in the EU?
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo do in cosmetics?
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreo functions as: Skin conditioning, anti-aging signal peptide. It is classified as a Active Ingredient in our database. CAS number: 883558-32-5.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Not Reported
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