Is PALLADIUM safe in cosmetics?
PALLADIUM has a safety rating of "GOOD" in our database. EU status: permitted. 2 toxicological study endpoint(s) are available in our database.
PALLADIUM
Also known as: EINECS 231-115-6, UNII-5TWQ1V240M, 46Pd, Pd
PALLADIUM (CAS 7440-05-3) is a cosmetic cosmetic ingredient functioning as Not Reported. Reported NOAEL =0.08 mg/kg bw (INCHEM_WHO_ehc_ehc_ehc226); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 7440-05-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
PALLADIUM is classified GHS Danger (H228, H315, H319, H335, H413) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Not Reported
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
palladium
InChIKey
KDLHZDBZIXYQEI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for PALLADIUM. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.08 mg/kg bw | - | - | Toxicology study | INCHEM_WHO_ehc_ehc_ehc226 |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (3)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Skin Eye Respiratory Irritation
Contact dermatitis has been associated with metallic palladium, especially with palladium alloys ... .
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for PALLADIUM.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PALLADIUM by CAS number or substance name.
Studies
2
Lowest NOAEL
0.08
Highest NOAEL
1000
Units vary across source rows: mg/kg bw, mg/kg bw/day
INCHEM_WHO_ehc_ehc_ehc226
ToxValDB_ECHA_IUCLID
Known Synonyms
EINECS 231-115-6
UNII-5TWQ1V240M
46Pd
Pd
Chemical Function
Dye
No specific technical function
Regulatory Lists
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PALLADIUM allowed in the EU?
PALLADIUM EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PALLADIUM do in cosmetics?
PALLADIUM functions as: Not Reported. It is classified as a cosmetic ingredient in our database. CAS number: 7440-05-3.
What is the NOAEL for PALLADIUM?
The NOAEL (No Observed Adverse Effect Level) for PALLADIUM is =0.08 mg/kg bw based on a Toxicology study study via oral route in rat. A total of 2 study endpoints are available. Source: INCHEM_WHO_ehc_ehc_ehc226.
Is PALLADIUM used outside cosmetics?
PALLADIUM also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does PALLADIUM have different safety status in cosmetics vs industrial chemicals?
PALLADIUM is classified GHS Danger (H228, H315, H319, H335, H413) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check PALLADIUM compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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