Is Nopol safe in cosmetics?
Nopol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Nopol
INCI: NOPOL
Nopol (CAS 128-50-7) is a cosmetic cosmetic ingredient functioning as Perfuming / fragrance ingredient with sweet, balsamic, pine, and citrus odor. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 128-50-7 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming / fragrance ingredient with sweet, balsamic, pine, and citrus odor
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl)ethanol
InChIKey
ROKSAUSPJGWCSM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FEMA GRAS; listed on EAFUS (Substances Added to Food)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Nopol.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5400 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
986
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
10-HYDROXYMETHYLENE-2-PINENE | 2008 | No safety concern at current levels of intake when used as a flavouring agent | TRS 952-JECFA 69 | FAS 50-JECFA 59/173
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
NOPOL | 2008 | No safety concern at current levels of intake when used as a flavouring agent | TRS 952-JECFA 69 | FAS 50-JECFA 59/173
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Nopol.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Nopol allowed in the EU?
Nopol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Nopol do in cosmetics?
Nopol functions as: Perfuming / fragrance ingredient with sweet, balsamic, pine, and citrus odor. It is classified as a cosmetic ingredient in our database. CAS number: 128-50-7.
Is Nopol used outside cosmetics?
Nopol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Nopol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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