NOAEL Data Cosmetic Ingredient

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-

CAS 128-50-7

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- (CAS 128-50-7) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Nopol →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-
CAS Number
128-50-7
DTXSID
DTXSID10861780
Molecular Formula
C11H18O
InChI Key
ROKSAUSPJGWCSM-UHFFFAOYSA-N
Monoisotopic Mass
166.135765

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
XK8HU7WJQCUNIIFDA UNII substance identifier--openFDA substances
XK8HU7WJQCUNIIFDA UNII substance identifier--openFDA substances
XK8HU7WJQCUNIIFDA UNII substance identifier--openFDA substances
XK8HU7WJQCUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
5400ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-?

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- has 7 NOAEL studies in the database. The lowest reported value is XK8HU7WJQC UNII. Source: openFDA substances.

What regulatory lists include Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-?

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- used in cosmetics?

Yes, Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- is also indexed as a cosmetic ingredient under the name Nopol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- used outside industrial chemicals?

Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl- also appears in cosmetics, food safety, cannabis databases.