Is NONYL ALCOHOL safe in cosmetics?
NONYL ALCOHOL has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed. 1 toxicological study endpoint(s) are available in our database.
NONYL ALCOHOL
Also known as: 4-01-00-01798, BRN 0969213, EINECS 205-583-7, Fatty alcohol(C9), FEMA No. 2789 (+7 more)
NONYL ALCOHOL (CAS 143-08-8) is a cosmetic cosmetic ingredient functioning as Perfuming. Reported NOAEL =1440 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 143-08-8 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
nonan-1-ol
InChIKey
ZWRUINPWMLAQRD-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — no restrictions; FEMA GRAS approved
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
1 study endpoint found for NONYL ALCOHOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1440 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1296 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Roberts Skin Permeation (Mendeley 2022)
MW: 144
Log Kow: 3.53
Log Kp: -1.2218487496163564
Log Jmax: -7.23
Source: Roberts_Cheruvu_Mendeley_2022
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Based on the eye irritation scores that were reported, 1-nonanol would be considered an eye irritant using the EU criteria.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (4)
JECFA Number
100
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ALCOHOL C-9 | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/29 | FAS 40-JECFA 49/147
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
PELARGONIC ALCOHOL | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/29 | FAS 40-JECFA 49/147
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
NONYL ALCOHOL | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/29 | FAS 40-JECFA 49/147
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NONYL ALCOHOL.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to NONYL ALCOHOL by CAS number or substance name.
Studies
1
Lowest NOAEL
1440 mg/kg bw/day
Highest NOAEL
1440 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
4-01-00-01798
BRN 0969213
EINECS 205-583-7
Fatty alcohol(C9)
FEMA No. 2789
UNII-NGK73Q6XMC
Acovenoside c
Alcohol C9
FEMA 2789
Nonyl alcohol, 8CI
nonan-1-ol
Nonanol
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
SCIL (9/2019)
Europe
Canada; pharmaceutical
air; detected; emissions; Europe; Toys and children's products
air; Cleaning products and household care - air freshener; detected; emissions; Europe
detected; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NONANOL
ChEMBL ID
CHEMBL24563
Frequently Asked Questions
Is NONYL ALCOHOL allowed in the EU?
NONYL ALCOHOL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NONYL ALCOHOL do in cosmetics?
NONYL ALCOHOL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 143-08-8.
What is the NOAEL for NONYL ALCOHOL?
The NOAEL (No Observed Adverse Effect Level) for NONYL ALCOHOL is =1440 mg/kg bw/day based on a developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is NONYL ALCOHOL used outside cosmetics?
NONYL ALCOHOL also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NONYL ALCOHOL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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