Is NONANAL safe in cosmetics?
NONANAL has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited. 2 toxicological study endpoint(s) are available in our database.
NONANAL
Also known as: C-9 aldehyde, 4-01-00-03352, BRN 1236701, EINECS 204-688-5, FEMA No. 2782 (+8 more)
NONANAL (CAS 124-19-6) is a cosmetic cosmetic ingredient functioning as Perfuming. Reported NOAEL =200 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 124-19-6 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
nonanal
InChIKey
GYHFUZHODSMOHU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Allowed — INCI name recognized for labeling under 21 CFR 701.3; not prohibited or restricted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for NONANAL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =200 mg/kg bw/day | oral | Rat | reproduction developmental | ECHA |
| NOAEL | =300 mg/kg bw/day | oral | Rat | reproduction developmental | ECHA |
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 648 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
fragrance
{"cas_number": "124-19-6", "ingredient_class": "aroma_chemical", "chemical_class": "aldehyde", "odor_family": "aldehydic", "odor_description": "Rosy, citrus, waxy, soapy", "odor_strength": "very_strong", "odor_tenacity_hours": "66.0", "top_note": "yes", "heart_note": "yes", "base_note": "no", "blending_factor_1_10": "10.0", "threshold_of_detection_ppb": "11.0", "molecular_weight_Da": "142", "boili…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Skin Eye Respiratory Irritation
A severe skin irritant.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (2)
JECFA Number
101
Source: WHO/JECFA
JECFA Evaluation
ALDEHYDE C-9 | 2002 | 0-0.1 mg/kg bw (1984) | No safety concern at current levels of intake when used as a flavouring agent; secondary components do not raise a safety concern. | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/147 (19970
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NONANAL.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
epa_safer_alternative
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to NONANAL by CAS number or substance name.
Studies
2
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
300 mg/kg bw/day
ECHA
Known Synonyms
C-9 aldehyde
4-01-00-03352
BRN 1236701
EINECS 204-688-5
FEMA No. 2782
NCI-C61018
n-Nonaldehyde
1-Nonaldehyde
Nonoic aldehyde
NONYL ALDEHYDE,N-
1-Nonyl aldehyde
UNII-2L2WBY9K6T
nonyl aldehyde
Chemical Function
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
air; Cons electronics mech appliances and machinery; detected; emissions; Europe
air; detected; emissions; Europe; Toys and children's products
air; Cleaning products and household care - air freshener; detected; emissions
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
air; detected; emissions; Europe; Toys and children's products
air; Cons electronics mech appliances and machinery; detected; emissions; Europe
detected; Europe; Other direct contact consumer goods
detected; Europe; Toys and children's products
detected; Europe; Toys and children's products
detected; Europe; Toys and children's products
Australia; Food and drug - smoking-related products
detected; Toys and children's products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
NONANAL
ADI
0-0.1 mg/kg bw (1984) mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is NONANAL allowed in the EU?
NONANAL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NONANAL do in cosmetics?
NONANAL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 124-19-6.
What is the NOAEL for NONANAL?
The NOAEL (No Observed Adverse Effect Level) for NONANAL is =200 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ECHA.
Is NONANAL used outside cosmetics?
NONANAL also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NONANAL compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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