Is NERYL ACETATE safe in cosmetics?
NERYL ACETATE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
Good
Cosmetic Ingredient
NERYL ACETATE
Also known as: 2-02-00-00153, BRN 1722814, cis-3,7-Dimethyl-2,6-octadien-1-ol acetate, 3,7-Dimethyl-2,6-octadienyl acetate, (Z)-, 3,7-Dimethyl-2,6-octadien-1-yl acetate, cis- (+7 more)
NERYL ACETATE (CAS 141-12-8) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 141-12-8 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
[(2Z)-3,7-dimethylocta-2,6-dienyl] acetate
InChIKey
HIGQPQRQIQDZMP-FLIBITNWSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — FEMA 2773; GRAS for flavor use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6480 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Regulatory (2)
JECFA Number
59
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
NERYL ACETATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/64 | FAS 40-JECFA 49/329
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NERYL ACETATE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
2-02-00-00153
BRN 1722814
cis-3,7-Dimethyl-2,6-octadien-1-ol acetate
3,7-Dimethyl-2,6-octadienyl acetate, (Z)-
3,7-Dimethyl-2,6-octadien-1-yl acetate, cis-
3,7-Dimethyl-2,6-octadien-1-yl ethanoate, cis-
EINECS 205-459-2
FEMA No. 2773
Geranyl acetate, cis-
Neryl ethanoate
NSC-72031
UNII-OF82IJU18H
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NERYL ACETATE
ChEMBL ID
CHEMBL2268549
Frequently Asked Questions
Is NERYL ACETATE allowed in the EU?
NERYL ACETATE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NERYL ACETATE do in cosmetics?
NERYL ACETATE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 141-12-8.
Is NERYL ACETATE used outside cosmetics?
NERYL ACETATE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NERYL ACETATE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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