Is Myristic Acid safe in cosmetics?
Myristic Acid has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Myristic Acid
Also known as: 4-02-00-01126, C14 fatty acid, BRN 0508624, EINECS 208-875-2, FEMA No. 2764 (+14 more)
INCI: MYRISTIC ACID
Myristic Acid (CAS 544-63-8) is a cosmetic cosmetic ingredient functioning as Surfactant, cleansing agent, emulsifier, emollient, opacifier. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 544-63-8 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant, cleansing agent, emulsifier, emollient, opacifier
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR safe as used (amended 2010). Formulations up to 13% non-sensitizing.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Myristic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
EPA ToxValDB — Toxicity Values
7 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| NOEL | =5 % w/v | Rat | dermal | acute | ECOTOX |
| NOEL | =5 % w/v | Rat | dermal | short-term | ECOTOX |
| NOEL | =5 % w/v | Rat | dermal | short-term | ECOTOX |
| NOEL | =5 % w/v | Rat | dermal | acute | ECOTOX |
| NOEL | =0.9 mM | European Rabbit | environmental | short-term | ECOTOX |
| NOEL | =0.09 mM | European Rabbit | environmental | short-term | ECOTOX |
| LD50 | >10000 mg/kg | Rat | oral | - | ChemIDplus |
Additional Ingredient Properties
7 property records from structured ingredient metadata.
baby_pediatric
{"cas_number": "CAS-FUNC-15", "ingredient_class": "other", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Fatty acid - natural, safe", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Functional ingre…
comedogenicity_detail
{"comedogenicity_rating": "3", "irritancy_rating": "2", "skin_type_suitability": "dry", "acne_safe": "no", "source": "Fulton 1989"}
deodorant
{"cas_number": "544-63-8", "ingredient_class": "other", "mechanism_of_action": "other", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "0", "odor_reduction_pct": "0", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "astringency_level": "varies…
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "15.5", "co_emulsifier_pairs": "sodium_hydroxide,triethanolamine", "optimal_oil_phase_pct": "10-28", "optimal_water_phase_pct": "72-90", "droplet_size_range_um": "5-35", "creaming_resistance": "moderate", "coalescence_resistance": "good", "ostwald_ripening_resistance": "moderate", "freeze_thaw_stability": "moderate", "rheology_modif…
regulatory
{"eu_status": "allowed", "us_status": "allowed"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_required": "13.0", "soluble_in": "oils, ethanol", "insoluble_in": "water, glycerin, propylene glycol", "log_p": "5.8", "melting_point_c": "54-56", "appearance": "white flakes", "source": "BASF"}
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Emulsifier
Flavouring and nutrient
Fragrance
Lubricating agent
No specific technical function
Opacifer
Plasticizer
Surfactant (surface active agent)
Regulatory List Membership (5)
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Myristic Acid.
Regulatory Flags
eu_children_restricted
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
4-02-00-01126
C14 fatty acid
BRN 0508624
EINECS 208-875-2
FEMA No. 2764
Hydrofol acid 1495
UNII-0I3V7S25AW
1-Tridecanecarboxylate
1-tetradecanecarboxylic acid
14
14:0
14:00
C14
CH3-[CH2]12-COOH
Crodacid
Myristate
Myristic acid pure
Myristoate
Myristoic acid
Chemical Function
Emulsifier
Fragrance
Cleaning agent
No specific technical function
Opacifer
Surfactant (surface active agent)
Flavouring and nutrient
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
active_ingredient; Europe; Pesticides
children; Europe; Personal care
Australia; Food and drug - smoking-related products
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; pharmaceutical
consumer_product
inert_ingredient; Pesticides
Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; Europe
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
detected; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
Europe
SCIL (9/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MYRISTIC ACID
ChEMBL ID
CHEMBL111077
Max Phase
-1
Frequently Asked Questions
Is Myristic Acid allowed in the EU?
Myristic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Myristic Acid do in cosmetics?
Myristic Acid functions as: Surfactant, cleansing agent, emulsifier, emollient, opacifier. It is classified as a cosmetic ingredient in our database. CAS number: 544-63-8.
Is Myristic Acid used outside cosmetics?
Myristic Acid also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Myristic Acid compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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