Is Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate safe in cosmetics?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
Also known as: Acetic acid, 2-cyano-2-[3-[(3-methoxypropyl)amino]-2-cyclohexen-1-ylidene]-, 2-ethoxyethyl ester, (2Z)-, 2-ethoxyethyl 2-cyano-2-[(1Z)-3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene]acetate, EC No.: 700-860-3
INCI: METHOXYPROPYLAMINO CYCLOHEXENYLIDENE ETHOXYETHYLCYANOACETATE
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate (CAS 1419401-88-9) is a cosmetic cosmetic ingredient functioning as UV Filter (absorbs UVA radiation); Light Stabilizer. NOAEL 250 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1419401-88-9 →
Auto-generated CPSR Part A draft with source citations
Function
UV Filter (absorbs UVA radiation); Light Stabilizer
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-ethoxyethyl (2Z)-2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate
InChIKey
NPNDSRGIZUPLNP-PEZBUJJGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not currently listed among FDA-approved OTC sunscreen actives (21 CFR 352); would require NDA or GRASE determination for sunscreen use in the US
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex VI — Permitted UV Filters
Max: 3%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: UV Filter. Max: 3%.
SA Saudi SFDA (VI - UV Filters)
Max: 0.03.
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.03
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | permitted_uv_filter | 3 | Sunscreen products |
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Aggregated DA Values (1 records across 5 sources)
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured_sccs_opinion | 2.65% | - | - | SCCS/1605/19 |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
sunscreen_uv
{"cas_number": "1419401-88-9", "uv_filter_type": "organic_UVA", "chemical_class": "other", "absorption_spectrum_nm_range": "340-400", "peak_absorption_wavelength_nm": "385", "molar_extinction_coefficient": "71000", "critical_wavelength_nm": "395", "UVA_PF": "28-46", "SPF_contribution_per_percent": "2.8", "photostability_rating": "photostable", "photodegradation_half_life_hours": ">24", "photostabi…
Expert Verdict
Expert safety assessment and concern-level summary for Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate.
Regulatory Flags
potential-allergen
Dermal Absorption
View details ->| Absorption % | Method | Vehicle |
|---|---|---|
| 2.65% | SCCS opinion extraction | - |
Known Synonyms
Acetic acid, 2-cyano-2-[3-[(3-methoxypropyl)amino]-2-cyclohexen-1-ylidene]-, 2-ethoxyethyl ester, (2Z)-
2-ethoxyethyl 2-cyano-2-[(1Z)-3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene]acetate
EC No.: 700-860-3
Frequently Asked Questions
Is Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate allowed in the EU?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate do in cosmetics?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate functions as: UV Filter (absorbs UVA radiation); Light Stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 1419401-88-9.
Is Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate used outside cosmetics?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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