Is Mercaptoisopropyl-5-Methylcyclohexanone safe in cosmetics?
Mercaptoisopropyl-5-Methylcyclohexanone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Mercaptoisopropyl-5-Methylcyclohexanone
Also known as: Cyclohexanone, 2-(1-mercapto-1-methylethyl)-5-methyl-, EINECS 253-953-1, FEMA No. 3177, 8-Mercapto-p-menthane-3-one, 8-Mercapto-p-menthan-3-one (+2 more)
INCI: MERCAPTOISOPROPYL-5-METHYLCYCLOHEXANONE
Mercaptoisopropyl-5-Methylcyclohexanone (CAS 38462-22-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient - sulfur-containing aroma compound contributing to perfume. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 38462-22-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient - sulfur-containing aroma compound contributing to perfume compositions.
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one
InChIKey
RVOKNSFEAOYULQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed in cosmetics as a fragrance component; no specific prohibition.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Mercaptoisopropyl-5-Methylcyclohexanone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
561
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
8-MERCAPTO-p-MENTHANE-3-ONE | 1999 | No safety concern at current levels of intake when used as a flavouring agent | TRS 896-JECFA 53/32 | FAS 44-JECFA 53/125
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
p-MENTHA-8-THIOL-3-ONE | 1999 | No safety concern at current levels of intake when used as a flavouring agent | TRS 896-JECFA 53/32 | FAS 44-JECFA 53/125
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Mercaptoisopropyl-5-Methylcyclohexanone.
Regulatory Flags
potential-allergen
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
Known Synonyms
Cyclohexanone, 2-(1-mercapto-1-methylethyl)-5-methyl-
EINECS 253-953-1
FEMA No. 3177
8-Mercapto-p-menthane-3-one
8-Mercapto-p-menthan-3-one
2-(1-Mercapto-1-methylethyl)-5-methylcyclohexanone
UNII-9BM9FFW27E
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
SCIL (9/2019)
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
P-MENTHA-8-THIOL-3-ONE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Mercaptoisopropyl-5-Methylcyclohexanone allowed in the EU?
Mercaptoisopropyl-5-Methylcyclohexanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mercaptoisopropyl-5-Methylcyclohexanone do in cosmetics?
Mercaptoisopropyl-5-Methylcyclohexanone functions as: Fragrance ingredient - sulfur-containing aroma compound contributing to perfume compositions.. It is classified as a cosmetic ingredient in our database. CAS number: 38462-22-5.
Is Mercaptoisopropyl-5-Methylcyclohexanone used outside cosmetics?
Mercaptoisopropyl-5-Methylcyclohexanone also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Mercaptoisopropyl-5-Methylcyclohexanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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