NOAEL Data Cosmetic Ingredient

P-Mentha-8-thiol-3-one

Also known as: Cyclohexanone, 2-(1-mercapto-1-methylethyl)-5-methyl-, EINECS 253-953-1, FEMA No. 3177, 8-Mercapto-p-menthane-3-one, 8-Mercapto-p-menthan-3-one (+2 more)

CAS 38462-22-5

P-Mentha-8-thiol-3-one (CAS 38462-22-5) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Mercaptoisopropyl-5-Methylcyclohexanone →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
5
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
P-Mentha-8-thiol-3-one
CAS Number
38462-22-5
DTXSID
DTXSID2047195
Molecular Formula
C10H18OS
InChI Key
RVOKNSFEAOYULQ-UHFFFAOYSA-N
Monoisotopic Mass
186.107836
Synonyms
Cyclohexanone, 2-(1-mercapto-1-methylethyl)-5-methyl-EINECS 253-953-1FEMA No. 31778-Mercapto-p-menthane-3-one8-Mercapto-p-menthan-3-one2-(1-Mercapto-1-methylethyl)-5-methylcyclohexanoneUNII-9BM9FFW27E

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
SCIL (9/2019)USEPASafer Chemical Ingredients List
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
9BM9FFW27EUNIIFDA UNII substance identifier--openFDA substances
9BM9FFW27EUNIIFDA UNII substance identifier--openFDA substances
9BM9FFW27EUNIIFDA UNII substance identifier--openFDA substances
9BM9FFW27EUNIIFDA UNII substance identifier--openFDA substances
=5mg/kg bw/dayLELoralChickenToxValDB_EFSA

Showing 5 of 5 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for P-Mentha-8-thiol-3-one?

P-Mentha-8-thiol-3-one has 5 NOAEL studies in the database. The lowest reported value is 9BM9FFW27E UNII. Source: openFDA substances.

What regulatory lists include P-Mentha-8-thiol-3-one?

P-Mentha-8-thiol-3-one appears on 5 regulatory/inventory lists including Europe, SCIL (9/2019), IFRA Transparency, and 2 more. Source: EPA CPDat.

Is P-Mentha-8-thiol-3-one used in cosmetics?

Yes, P-Mentha-8-thiol-3-one is also indexed as a cosmetic ingredient under the name Mercaptoisopropyl-5-Methylcyclohexanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for P-Mentha-8-thiol-3-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is P-Mentha-8-thiol-3-one used outside industrial chemicals?

P-Mentha-8-thiol-3-one also appears in cosmetics, food safety, cannabis databases.