Is Konjac Glucomannan safe in cosmetics?
Konjac Glucomannan has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Active Ingredient
Konjac Glucomannan
INCI: KONJAC GLUCOMANNAN
Konjac Glucomannan (CAS 37220-17-0) is a cosmetic active ingredient functioning as Prebiotic, C. acnes Inhibition (synbiotic), Microbiome Support, Film Former,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 37220-17-0 →
Auto-generated CPSR Part A draft with source citations
Function
Prebiotic, C. acnes Inhibition (synbiotic), Microbiome Support, Film Former, Skin Conditioning, Humectant
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as cosmetic ingredient. Prebiotic C. acnes inhibition positioning is cosmetic-appropriate (improving skin appearance). Direct acne treatment claims = drug. MoCRA 2026 compliance required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Konjac Glucomannan.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Konjac Glucomannan.
Regulatory Flags
prebiotic
microbiome-friendly
no-live-organisms
c-acnes-inhibition-synbiotic
acne-prone-positioning
hydrolysate-form-prebiotic-active
synbiotic-combination-required
film-former-intact-form
inci-disambiguation-hydrolysate-vs-polymer
plant-derived
cosmos-ecocert-compatible
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
48
Frequently Asked Questions
Is Konjac Glucomannan allowed in the EU?
Konjac Glucomannan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Konjac Glucomannan do in cosmetics?
Konjac Glucomannan functions as: Prebiotic, C. acnes Inhibition (synbiotic), Microbiome Support, Film Former, Skin Conditioning, Humectant. It is classified as a Active Ingredient in our database. CAS number: 37220-17-0.
Is Konjac Glucomannan used outside cosmetics?
Konjac Glucomannan also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Konjac Glucomannan compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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