Is Isopropyl Phenylacetaldehyde safe in cosmetics?
Isopropyl Phenylacetaldehyde has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Isopropyl Phenylacetaldehyde
Also known as: Methylethyl)benzeneacetaldehyde, Benzeneacetaldehyde, 4-(1-methylethyl)-, Acetaldehyde, (p-isopropylphenyl)-, p-Cymene-7-carboxaldehyde, 4-(1-Methylethyl)benzeneacetaldehyde (+11 more)
INCI: ISOPROPYL PHENYLACETALDEHYDE (ALSO LISTED AS AR-ISOPROPYLPHENYLACETALDEHYDE)
Isopropyl Phenylacetaldehyde (CAS 4395-92-0) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent); declared as "PARFUM" on product labels. EU Regulation 1223/2009 status: restricted, max 0.004%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 4395-92-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming agent); declared as "PARFUM" on product labels
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.004%
US US Status
permitted
US Notes
Allowed - listed in the FDA Substances Added to Food (formerly EAFUS) database; no specific prohibition for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isopropyl Phenylacetaldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Isopropyl Phenylacetaldehyde.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Methylethyl)benzeneacetaldehyde
Benzeneacetaldehyde, 4-(1-methylethyl)-
Acetaldehyde, (p-isopropylphenyl)-
p-Cymene-7-carboxaldehyde
4-(1-Methylethyl)benzeneacetaldehyde
4-Isopropylphenylacetaldehyde
4-07-00-00747
BRN 2246668
Cortexal
Cuminic acetaldehyde
Cumyl acetaldehyde
Cumylacetaldehyde
EINECS 224-522-5
FEMA No. 2954
p-Isopropylphenylacetaldehyde
UNII-5KQW56W3YJ
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
consumer_product
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isopropyl Phenylacetaldehyde allowed in the EU?
Isopropyl Phenylacetaldehyde EU regulatory status: restricted. Maximum allowed concentration: 0.004%. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropyl Phenylacetaldehyde do in cosmetics?
Isopropyl Phenylacetaldehyde functions as: Fragrance (perfuming agent); declared as "PARFUM" on product labels. It is classified as a cosmetic ingredient in our database. CAS number: 4395-92-0.
Compliance Tools
Check Isopropyl Phenylacetaldehyde compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
Ar-Isopropylphenylacetaldehyde
Good
Chemical family
Fragrance
Cuminyl Nitrile
Moderate
Chemical family
Perfuming
ISOBORNYL DIPROPYLENE GLYCOL ETHERS
Good
Browse nearby
Antifoaming, Emulsion Stabilising, So...
Is Isopropyl Phenylacetaldehyde in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isopropyl Phenylacetaldehyde in your formulation.