What is the NOAEL for 4-Isopropylphenylacetaldehyde?
4-Isopropylphenylacetaldehyde has 9 NOAEL studies in the database. The lowest reported value is 5KQW56W3YJ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
4-Isopropylphenylacetaldehyde
Also known as: Methylethyl)benzeneacetaldehyde, Benzeneacetaldehyde, 4-(1-methylethyl)-, Acetaldehyde, (p-isopropylphenyl)-, p-Cymene-7-carboxaldehyde, 4-(1-Methylethyl)benzeneacetaldehyde (+10 more)
CAS 4395-92-0
4-Isopropylphenylacetaldehyde (CAS 4395-92-0) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Ar-Isopropylphenylacetaldehyde →
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
4-Isopropylphenylacetaldehyde
CAS Number
4395-92-0
DTXSID
DTXSID2052102
Molecular Formula
C12H16
InChI Key
QBLYEXXCHLBGNO-UHFFFAOYSA-N
Monoisotopic Mass
160.125201
Synonyms
Methylethyl)benzeneacetaldehydeBenzeneacetaldehyde, 4-(1-methylethyl)-Acetaldehyde, (p-isopropylphenyl)-p-Cymene-7-carboxaldehyde4-(1-Methylethyl)benzeneacetaldehyde4-07-00-00747BRN 2246668CortexalCuminic acetaldehydeCumyl acetaldehydeCumylacetaldehydeEINECS 224-522-5
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5KQW56W3YJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KQW56W3YJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KQW56W3YJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KQW56W3YJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =4100 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 19 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 4-Isopropylphenylacetaldehyde?
4-Isopropylphenylacetaldehyde appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, consumer_product, and 1 more. Source: EPA CPDat.
Is 4-Isopropylphenylacetaldehyde used in cosmetics?
Yes, 4-Isopropylphenylacetaldehyde is also indexed as a cosmetic ingredient under the name Ar-Isopropylphenylacetaldehyde. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Isopropylphenylacetaldehyde come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Isopropylphenylacetaldehyde used outside industrial chemicals?
4-Isopropylphenylacetaldehyde also appears in cosmetics, cannabis databases.