Is Hydroxyphenyl Dihydroxybenzamide safe in cosmetics?
Hydroxyphenyl Dihydroxybenzamide has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hydroxyphenyl Dihydroxybenzamide
Also known as: N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide
INCI: HYDROXYPHENYL DIHYDROXYBENZAMIDE
Hydroxyphenyl Dihydroxybenzamide (CAS 66612-11-1) is a cosmetic cosmetic ingredient functioning as Antioxidant; skin protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 66612-11-1 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant; skin protecting
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
N-[2-[(2-chloro-4-oxocyclohexa-2,5-dien-1-ylidene)amino]-5-hydroxy-4-methoxyphenyl]acetamide
InChIKey
DNCKSSGISBCYQW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific CFR restriction; no CIR review identified
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxyphenyl Dihydroxybenzamide.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1304
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1304
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Hydroxyphenyl Dihydroxybenzamide.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Frequently Asked Questions
Is Hydroxyphenyl Dihydroxybenzamide allowed in the EU?
Hydroxyphenyl Dihydroxybenzamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyphenyl Dihydroxybenzamide do in cosmetics?
Hydroxyphenyl Dihydroxybenzamide functions as: Antioxidant; skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 66612-11-1.
Compliance Tools
Check Hydroxyphenyl Dihydroxybenzamide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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