NOAEL Data Cosmetic Ingredient

HC Yellow 8

Also known as: N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide

CAS 66612-11-1

HC Yellow 8 (CAS 66612-11-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for HC Yellow No. 8 →

SOURCE noael studies public
NOAEL studies
3
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
HC Yellow 8
CAS Number
66612-11-1
DTXSID
DTXSID70879806
Molecular Formula
C15H13ClN2O4
InChI Key
GZTWJLFQKINBCF-QGOAFFKASA-N
Monoisotopic Mass
320.056385
Synonyms
N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
banned; Europe; Personal careEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 3 of 3 studies
ValueUnitEndpointRouteSpeciesSource
F1NQ5U8325UNIIFDA UNII substance identifier--openFDA substances
F1NQ5U8325UNIIFDA UNII substance identifier--openFDA substances
F1NQ5U8325UNIIFDA UNII substance identifier--openFDA substances

Showing 3 of 3 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for HC Yellow 8?

HC Yellow 8 has 3 NOAEL studies in the database. The lowest reported value is F1NQ5U8325 UNII. Source: openFDA substances.

What regulatory lists include HC Yellow 8?

HC Yellow 8 appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.

Is HC Yellow 8 used in cosmetics?

Yes, HC Yellow 8 is also indexed as a cosmetic ingredient under the name HC Yellow No. 8. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for HC Yellow 8 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is HC Yellow 8 used outside industrial chemicals?

HC Yellow 8 also appears in cosmetics databases.