Is Hexenyl Tiglate safe in cosmetics?
Hexenyl Tiglate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hexenyl Tiglate
Also known as: BRN 2961441, EINECS 267-554-5, cis-Hex-3-ene-1-yl trans-2-methyl-2-butenoate, cis-3-Hexenyl tiglate, cis-3-Hexenyl-2-methyl-trans-2-butenoate (+2 more)
INCI: HEXENYL TIGLATE
Hexenyl Tiglate (CAS 67883-79-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient with green, fruity top note characteristics. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 67883-79-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient with green, fruity top note characteristics
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(Z)-hex-3-enyl] (E)-2-methylbut-2-enoate
InChIKey
JNWQKXUWZWKUAY-JQEGGOPCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted, not restricted under 21 CFR. RIFM safety assessment completed.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexenyl Tiglate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
cis-3-HEXENYL TIGLATE | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/101 | FAS 42-JECFA 51/267 (1998)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Hexenyl Tiglate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
BRN 2961441
EINECS 267-554-5
cis-Hex-3-ene-1-yl trans-2-methyl-2-butenoate
cis-3-Hexenyl tiglate
cis-3-Hexenyl-2-methyl-trans-2-butenoate
(E,Z)-2-Methyl-2-butenoic acid 3-hexenyl ester
UNII-9S19N7N2QK
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
consumer_product
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183070
Frequently Asked Questions
Is Hexenyl Tiglate allowed in the EU?
Hexenyl Tiglate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexenyl Tiglate do in cosmetics?
Hexenyl Tiglate functions as: Fragrance ingredient with green, fruity top note characteristics. It is classified as a cosmetic ingredient in our database. CAS number: 67883-79-8.
Is Hexenyl Tiglate used outside cosmetics?
Hexenyl Tiglate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexenyl Tiglate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
cis-3-Hexenyl Tiglate
Moderate
Chemical family
Fragrance ingredient (green, fruity, ...
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE
Good
Browse nearby
Perfuming
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE-8-METHANOL
Good
Browse nearby
Perfuming
Is Hexenyl Tiglate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hexenyl Tiglate in your formulation.