NOAEL Data Cosmetic Ingredient

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate

Also known as: BRN 2961441, EINECS 267-554-5, cis-Hex-3-ene-1-yl trans-2-methyl-2-butenoate, cis-3-Hexenyl tiglate, cis-3-Hexenyl-2-methyl-trans-2-butenoate (+2 more)

CAS 67883-79-8

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate (CAS 67883-79-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for cis-3-Hexenyl Tiglate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields

Name

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate

CAS Number

67883-79-8

DTXSID

DTXSID7047562

Molecular Formula

C11H18O2

InChI Key

JNWQKXUWZWKUAY-JQEGGOPCSA-N

Monoisotopic Mass

182.13068

Synonyms

BRN 2961441EINECS 267-554-5cis-Hex-3-ene-1-yl trans-2-methyl-2-butenoatecis-3-Hexenyl tiglatecis-3-Hexenyl-2-methyl-trans-2-butenoate(E,Z)-2-Methyl-2-butenoic acid 3-hexenyl esterUNII-9S19N7N2QK

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 12 records

FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records

List	Keyword	Source
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)
IFRA Transparency	IFRA	IFRA
consumer_product	P&G	Proctor & Gamble
Europe	European Commission	Fl@vis

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies

Value	Unit	Endpoint	Route	Species	Source
9S19N7N2QK	UNII	FDA UNII substance identifier	-	-	openFDA substances
9S19N7N2QK	UNII	FDA UNII substance identifier	-	-	openFDA substances
9S19N7N2QK	UNII	FDA UNII substance identifier	-	-	openFDA substances
9S19N7N2QK	UNII	FDA UNII substance identifier	-	-	openFDA substances
-	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
8100	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
>5000	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
3	unitless	Relative reliability score	Dermal	Human	NTP_ICE_skin_sensitization

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3183070

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate?

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate has 8 NOAEL studies in the database. The lowest reported value is 9S19N7N2QK UNII. Source: openFDA substances.

What regulatory lists include (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate?

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate appears on 4 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency, consumer_product, and 1 more. Source: EPA CPDat.

Is (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate used in cosmetics?

Yes, (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate is also indexed as a cosmetic ingredient under the name cis-3-Hexenyl Tiglate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is (3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate used outside industrial chemicals?

(3Z)-Hex-3-en-1-yl (2E)-2-methylbut-2-enoate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.