Is Hexahydro-dimethylspiromethanonaphthalene-oxirane safe in cosmetics?
Hexahydro-dimethylspiromethanonaphthalene-oxirane has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Hexahydro-dimethylspiromethanonaphthalene-oxirane
Also known as: EINECS 255-560-0, 3,4,4a,5,8,8a-Hexahydro-3',7
INCI: HEXAHYDRO-DIMETHYLSPIROMETHANONAPHTHALENE-OXIRANE
Hexahydro-dimethylspiromethanonaphthalene-oxirane (CAS 41816-03-9) is a cosmetic cosmetic ingredient functioning as Fragrance agent (perfuming). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 41816-03-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Hexahydro-dimethylspiromethanonaphthalene-oxirane is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Fragrance agent (perfuming)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
3,4'-dimethylspiro[oxirane-2,10'-tricyclo[6.2.1.02,7]undec-4-ene]
InChIKey
VKPRTBDRPNWOGL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexahydro-dimethylspiromethanonaphthalene-oxirane.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | - | 0 | - | - | - |
| HRIPT | - | 0 | - | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Hexahydro-dimethylspiromethanonaphthalene-oxirane.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
Known Synonyms
EINECS 255-560-0
3,4,4a,5,8,8a-Hexahydro-3',7
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Hexahydro-dimethylspiromethanonaphthalene-oxirane allowed in the EU?
Hexahydro-dimethylspiromethanonaphthalene-oxirane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexahydro-dimethylspiromethanonaphthalene-oxirane do in cosmetics?
Hexahydro-dimethylspiromethanonaphthalene-oxirane functions as: Fragrance agent (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 41816-03-9.
Is Hexahydro-dimethylspiromethanonaphthalene-oxirane used outside cosmetics?
Hexahydro-dimethylspiromethanonaphthalene-oxirane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Hexahydro-dimethylspiromethanonaphthalene-oxirane have different safety status in cosmetics vs industrial chemicals?
Hexahydro-dimethylspiromethanonaphthalene-oxirane is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check Hexahydro-dimethylspiromethanonaphthalene-oxirane compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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